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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NKAPL All Species: 12.12
Human Site: S170 Identified Species: 26.67
UniProt: Q5M9Q1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5M9Q1 NP_001007532.1 402 46240 S170 Q K S S S S D S N S E E H R K
Chimpanzee Pan troglodytes XP_518308 399 45889 S170 Q K S S S S D S N S E E H R K
Rhesus Macaque Macaca mulatta XP_001099236 405 46727 S172 Q K R S G S D S N S E E H R K
Dog Lupus familis XP_549220 345 38782 S122 K K K K S G H S K E R S K K R
Cat Felis silvestris
Mouse Mus musculus Q9D0F4 415 47209 E177 T T S A S S S E D D K K K K R
Rat Rattus norvegicus Q4V7C9 415 47248 E177 T T S A S S S E D D K K K K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006437 361 41644 R138 S S S E E E K R K K K K K R K
Frog Xenopus laevis NP_001090505 326 37784 E103 I G E L G A P E V W G L S P K
Zebra Danio Brachydanio rerio NP_001003414 368 43163 S145 E E D V K N S S S D S S S E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VB74 463 52929 K225 K H K K S E K K S K K K S K K
Honey Bee Apis mellifera XP_391898 247 28438 P24 D R I W G K S P T R I E D S D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97 88.4 58.4 N.A. 62.1 62.6 N.A. N.A. 62.4 51.4 54.4 N.A. 36 35 N.A. N.A.
Protein Similarity: 100 98.5 91.3 68.9 N.A. 72 71.5 N.A. N.A. 70.1 60.9 68.6 N.A. 49.2 47.2 N.A. N.A.
P-Site Identity: 100 100 86.6 20 N.A. 20 20 N.A. N.A. 20 6.6 6.6 N.A. 13.3 6.6 N.A. N.A.
P-Site Similarity: 100 100 86.6 40 N.A. 60 60 N.A. N.A. 33.3 13.3 40 N.A. 46.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 0 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 0 0 28 0 19 28 0 0 10 0 10 % D
% Glu: 10 10 10 10 10 19 0 28 0 10 28 37 0 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 28 10 0 0 0 0 10 0 0 0 0 % G
% His: 0 10 0 0 0 0 10 0 0 0 0 0 28 0 0 % H
% Ile: 10 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 19 37 19 19 10 10 19 10 19 19 37 37 37 37 55 % K
% Leu: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 28 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 10 10 0 0 0 0 0 10 0 % P
% Gln: 28 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 10 0 0 0 0 10 0 10 10 0 0 37 28 % R
% Ser: 10 10 46 28 55 46 37 46 19 28 10 19 28 10 0 % S
% Thr: 19 19 0 0 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _