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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC158 All Species: 19.39
Human Site: S394 Identified Species: 47.41
UniProt: Q5M9N0 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5M9N0 NP_001036249.1 1113 127140 S394 H K R E K E L S L E K E Q N K
Chimpanzee Pan troglodytes XP_001148738 1112 126890 S393 H K R E K E L S L E K E Q N K
Rhesus Macaque Macaca mulatta XP_001095126 1113 127236 S394 H K R E K E L S L E K E Q N K
Dog Lupus familis XP_535613 1118 127721 S394 H K R E K E L S L E K E Q N K
Cat Felis silvestris
Mouse Mus musculus Q8CDI6 1109 126807 S393 H K R E K E L S L E K E Q N K
Rat Rattus norvegicus Q66HR5 691 77257 K52 S D W I G I F K V E A A C V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517668 582 67861
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920098 2370 276418 E1139 H R R D L G E E L E A L K T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797547 1503 168639 T514 E T Y A S L T T Q L N E E K E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06704 911 105207 E272 E L E K K M K E L P K A I S H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.4 92.6 N.A. 92 21.1 N.A. 39.3 N.A. N.A. 20.6 N.A. N.A. N.A. N.A. 22
Protein Similarity: 100 99.7 99 95.8 N.A. 95.6 37.2 N.A. 47.1 N.A. N.A. 33.9 N.A. N.A. N.A. N.A. 41.4
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 0 N.A. N.A. 26.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 0 N.A. N.A. 53.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 20 20 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 20 0 10 50 0 50 10 20 0 70 0 60 10 0 20 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % G
% His: 60 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 10 0 10 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 50 0 10 60 0 10 10 0 0 60 0 10 10 50 % K
% Leu: 0 10 0 0 10 10 50 0 70 10 0 10 0 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 0 0 50 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 50 0 0 % Q
% Arg: 0 10 60 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 10 0 0 0 10 0 0 50 0 0 0 0 0 10 0 % S
% Thr: 0 10 0 0 0 0 10 10 0 0 0 0 0 10 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _