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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TECRL All Species: 24.24
Human Site: S123 Identified Species: 48.48
UniProt: Q5HYJ1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5HYJ1 NP_001010874.2 363 42009 S123 K D Y I T I Q S I A A S S I V
Chimpanzee Pan troglodytes XP_001165357 363 41943 S123 K D Y V T I Q S I A A S S I V
Rhesus Macaque Macaca mulatta XP_001110088 363 41911 S123 K D Y I T I Q S I A A S S I V
Dog Lupus familis XP_532387 363 41994 S123 K D Y I T V Q S I A A S S I V
Cat Felis silvestris
Mouse Mus musculus Q8BFZ1 361 41874 S121 R D Y I T V Q S V A A S S I I
Rat Rattus norvegicus Q64232 308 36104 Y77 V G T T A T L Y F R D L G A Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511037 363 41640 S123 K D S V S I Q S L A A S S I V
Chicken Gallus gallus
Frog Xenopus laevis NP_001080461 308 36103 Y77 V G T T A T L Y F R D L G A Q
Zebra Danio Brachydanio rerio NP_958456 308 36259 Y77 V G T T A T F Y F R D L G A Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781465 374 42420 S135 K G D D T L G S L G I T H G D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38944 262 30616 Q32 A V L L K F L Q A P Y G K H N
Baker's Yeast Sacchar. cerevisiae Q99190 310 36749 P80 F F I K D L G P Q I S W R L V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.8 86.2 N.A. 82 43.2 N.A. 76.8 N.A. 45.4 44 N.A. N.A. N.A. N.A. 37.4
Protein Similarity: 100 99.7 98.6 92.5 N.A. 90 57.8 N.A. 88.4 N.A. 59.2 59.2 N.A. N.A. N.A. N.A. 56.1
P-Site Identity: 100 93.3 100 93.3 N.A. 73.3 0 N.A. 73.3 N.A. 0 0 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 100 0 N.A. 93.3 N.A. 0 0 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. 23.6 21.4 N.A.
Protein Similarity: N.A. N.A. N.A. 34.9 35.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 25 0 0 0 9 50 50 0 0 25 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 50 9 9 9 0 0 0 0 0 25 0 0 0 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 9 9 0 0 0 9 9 0 25 0 0 0 0 0 0 % F
% Gly: 0 34 0 0 0 0 17 0 0 9 0 9 25 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 9 0 % H
% Ile: 0 0 9 34 0 34 0 0 34 9 9 0 0 50 9 % I
% Lys: 50 0 0 9 9 0 0 0 0 0 0 0 9 0 0 % K
% Leu: 0 0 9 9 0 17 25 0 17 0 0 25 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 9 0 9 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 50 9 9 0 0 0 0 0 25 % Q
% Arg: 9 0 0 0 0 0 0 0 0 25 0 0 9 0 0 % R
% Ser: 0 0 9 0 9 0 0 59 0 0 9 50 50 0 0 % S
% Thr: 0 0 25 25 50 25 0 0 0 0 0 9 0 0 0 % T
% Val: 25 9 0 17 0 17 0 0 9 0 0 0 0 0 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 42 0 0 0 0 25 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _