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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARL13A All Species: 24.24
Human Site: Y146 Identified Species: 33.33
UniProt: Q5H913 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5H913 NP_001155963 297 33799 Y146 M P C D I I D Y L L L K K L V
Chimpanzee Pan troglodytes XP_521175 308 35266 Y146 M P C D I I D Y L L L K K L V
Rhesus Macaque Macaca mulatta XP_001090836 297 33776 Y146 M P C D I I D Y L L L K K L V
Dog Lupus familis XP_545056 443 50183 C159 G E A D V I E C L S L E K L V
Cat Felis silvestris
Mouse Mus musculus Q9D416 372 43445 Y146 L P C D I I E Y L L L E R L V
Rat Rattus norvegicus Q6AXT3 395 45449 Y146 L P C D I I E Y L L L E R L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514970 442 50454 C155 A E A D V I E C L S L E K L V
Chicken Gallus gallus XP_416642 425 48393 T146 S E A D V I E T L S L E K L V
Frog Xenopus laevis Q8QHI3 182 20390 G50 S H I T P T Q G F N I K S V Q
Zebra Danio Brachydanio rerio Q8JHI3 407 46548 T146 A E A D I I E T L S L E K L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q06849 184 20816 I52 S P T L G F N I K T L E H N G
Honey Bee Apis mellifera XP_394559 184 21013 I52 S P T L G F N I K T L E H R G
Nematode Worm Caenorhab. elegans O45379 184 20752 N52 V T P T K G F N V K T V A A M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002310807 185 21192 K53 P T L G F N I K T I S Y Q K Y
Maize Zea mays NP_001149177 185 21154 K53 P T L G F N I K T I K Y H K Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZPX1 185 21059 K53 P T L G F N I K T I I Y Q K Y
Baker's Yeast Sacchar. cerevisiae P40994 183 20678 F51 T S T P T V G F N V E T V T Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.5 95.6 25.7 N.A. 47.8 48 N.A. 26.7 28.2 22.5 27 N.A. 24.2 24.5 21.5 N.A.
Protein Similarity: 100 93.8 97.3 41.3 N.A. 62 59.4 N.A. 40.2 44 37.3 44.2 N.A. 36.7 38.3 35.6 N.A.
P-Site Identity: 100 100 100 46.6 N.A. 73.3 73.3 N.A. 46.6 46.6 6.6 53.3 N.A. 13.3 13.3 0 N.A.
P-Site Similarity: 100 100 100 66.6 N.A. 100 100 N.A. 66.6 66.6 20 66.6 N.A. 26.6 26.6 20 N.A.
Percent
Protein Identity: 25.2 24.2 N.A. 25.5 21.5 N.A.
Protein Similarity: 40.4 40.4 N.A. 41 37 N.A.
P-Site Identity: 0 0 N.A. 0 0 N.A.
P-Site Similarity: 13.3 6.6 N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 24 0 0 0 0 0 0 0 0 0 6 6 0 % A
% Cys: 0 0 30 0 0 0 0 12 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 53 0 0 18 0 0 0 0 0 0 0 0 % D
% Glu: 0 24 0 0 0 0 36 0 0 0 6 48 0 0 0 % E
% Phe: 0 0 0 0 18 12 6 6 6 0 0 0 0 0 0 % F
% Gly: 6 0 0 18 12 6 6 6 0 0 0 0 0 0 12 % G
% His: 0 6 0 0 0 0 0 0 0 0 0 0 18 0 0 % H
% Ile: 0 0 6 0 36 53 18 12 0 18 12 0 0 0 0 % I
% Lys: 0 0 0 0 6 0 0 18 12 6 6 24 42 18 0 % K
% Leu: 12 0 18 12 0 0 0 0 53 30 65 0 0 53 0 % L
% Met: 18 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % M
% Asn: 0 0 0 0 0 18 12 6 6 6 0 0 0 6 0 % N
% Pro: 18 42 6 6 6 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 6 0 0 0 0 0 12 0 6 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 12 6 0 % R
% Ser: 24 6 0 0 0 0 0 0 0 24 6 0 6 0 0 % S
% Thr: 6 24 18 12 6 6 0 12 18 12 6 6 0 6 0 % T
% Val: 6 0 0 0 18 6 0 0 6 6 0 6 6 6 53 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 30 0 0 0 18 0 0 24 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _