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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XKR4
All Species:
17.88
Human Site:
S593
Identified Species:
35.76
UniProt:
Q5GH76
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5GH76
NP_443130.1
650
71501
S593
R
P
P
R
I
E
E
S
V
I
K
I
D
L
F
Chimpanzee
Pan troglodytes
Q49LS4
650
71542
S593
R
P
P
R
I
E
E
S
V
I
K
I
D
L
F
Rhesus Macaque
Macaca mulatta
XP_001089696
798
88712
G727
S
G
S
I
D
K
S
G
V
L
Q
I
D
F
S
Dog
Lupus familis
XP_851429
553
62922
S496
R
L
P
R
I
E
E
S
V
I
K
I
D
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q5GH67
647
71484
S590
R
P
P
R
I
E
E
S
V
I
K
I
D
L
F
Rat
Rattus norvegicus
Q5GH59
647
72697
S590
R
P
P
R
I
E
E
S
V
I
K
I
D
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514351
544
61442
V488
P
P
R
I
E
E
S
V
I
K
I
D
L
F
R
Chicken
Gallus gallus
XP_001235083
471
53365
I415
P
R
T
E
G
P
V
I
R
I
D
L
P
R
K
Frog
Xenopus laevis
NP_001086032
361
41174
I305
P
R
A
Q
G
P
V
I
R
I
D
L
P
R
K
Zebra Danio
Brachydanio rerio
NP_001012258
612
69146
V556
A
P
R
L
E
E
T
V
I
K
I
D
L
C
R
Tiger Blowfish
Takifugu rubipres
NP_001027884
578
66196
I522
I
Q
P
E
G
P
F
I
K
I
D
M
P
R
K
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789903
551
64029
R495
L
F
S
Y
K
W
R
R
H
I
H
P
E
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
37.8
82.4
N.A.
95.5
79.2
N.A.
73.5
42.9
31.3
75.8
44.1
N.A.
N.A.
N.A.
31
Protein Similarity:
100
99.5
50.2
83
N.A.
96.7
82
N.A.
77
53.2
40.9
82.7
58.1
N.A.
N.A.
N.A.
45.3
P-Site Identity:
100
100
20
93.3
N.A.
100
100
N.A.
13.3
6.6
6.6
13.3
13.3
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
40
93.3
N.A.
100
100
N.A.
20
13.3
20
20
20
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
25
17
50
0
0
% D
% Glu:
0
0
0
17
17
59
42
0
0
0
0
0
9
0
0
% E
% Phe:
0
9
0
0
0
0
9
0
0
0
0
0
0
17
42
% F
% Gly:
0
9
0
0
25
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% H
% Ile:
9
0
0
17
42
0
0
25
17
75
17
50
0
0
0
% I
% Lys:
0
0
0
0
9
9
0
0
9
17
42
0
0
0
25
% K
% Leu:
9
9
0
9
0
0
0
0
0
9
0
17
17
50
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
25
50
50
0
0
25
0
0
0
0
0
9
25
0
0
% P
% Gln:
0
9
0
9
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
42
17
17
42
0
0
9
9
17
0
0
0
0
25
17
% R
% Ser:
9
0
17
0
0
0
17
42
0
0
0
0
0
0
9
% S
% Thr:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
17
17
50
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _