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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XKR4 All Species: 10.61
Human Site: S581 Identified Species: 21.21
UniProt: Q5GH76 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5GH76 NP_443130.1 650 71501 S581 Q V R P T A P S T P S S R P P
Chimpanzee Pan troglodytes Q49LS4 650 71542 S581 Q V R P T A P S T P S S R P P
Rhesus Macaque Macaca mulatta XP_001089696 798 88712 A715 H S L I T C E A N V D H S G S
Dog Lupus familis XP_851429 553 62922 S484 Q V R P T A P S T P S S R L P
Cat Felis silvestris
Mouse Mus musculus Q5GH67 647 71484 P578 Q V R P T A P P T P S S R P P
Rat Rattus norvegicus Q5GH59 647 72697 P578 Q V R P T A P P T P S S R P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514351 544 61442 T476 V R P T A P S T P S S R P P R
Chicken Gallus gallus XP_001235083 471 53365 P403 R P C A P T P P A A R A P R T
Frog Xenopus laevis NP_001086032 361 41174 P293 R P S V P P T P I T R L P R A
Zebra Danio Brachydanio rerio NP_001012258 612 69146 T544 V R P T A P S T P S S R A P R
Tiger Blowfish Takifugu rubipres NP_001027884 578 66196 A510 R S T E P V D A A G R P I Q P
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789903 551 64029 R483 R K M S E R D R Y Y A N L F S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 37.8 82.4 N.A. 95.5 79.2 N.A. 73.5 42.9 31.3 75.8 44.1 N.A. N.A. N.A. 31
Protein Similarity: 100 99.5 50.2 83 N.A. 96.7 82 N.A. 77 53.2 40.9 82.7 58.1 N.A. N.A. N.A. 45.3
P-Site Identity: 100 100 6.6 93.3 N.A. 93.3 93.3 N.A. 13.3 6.6 0 13.3 6.6 N.A. N.A. N.A. 0
P-Site Similarity: 100 100 13.3 93.3 N.A. 93.3 93.3 N.A. 20 20 6.6 20 20 N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 17 42 0 17 17 9 9 9 9 0 9 % A
% Cys: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 17 0 0 0 9 0 0 0 0 % D
% Glu: 0 0 0 9 9 0 9 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 0 9 0 0 0 9 0 0 % I
% Lys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 9 0 0 0 0 0 0 0 0 9 9 9 0 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % N
% Pro: 0 17 17 42 25 25 50 34 17 42 0 9 25 50 50 % P
% Gln: 42 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 34 17 42 0 0 9 0 9 0 0 25 17 42 17 17 % R
% Ser: 0 17 9 9 0 0 17 25 0 17 59 42 9 0 17 % S
% Thr: 0 0 9 17 50 9 9 17 42 9 0 0 0 0 9 % T
% Val: 17 42 0 9 0 9 0 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _