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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FLG2 All Species: 5.76
Human Site: S499 Identified Species: 31.67
UniProt: Q5D862 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5D862 NP_001014364.1 2391 248073 S499 F G Q C G S G S G Q S S G F G
Chimpanzee Pan troglodytes XP_524874 2857 282705 S498 H G Q H G S R S G Q S S R G E
Rhesus Macaque Macaca mulatta XP_001109011 2265 236397 C453 V A G S S Q T C S Q Y G S R S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q2VIS4 2362 251353 S501 S G R H G S G S G Q S S S S R
Rat Rattus norvegicus XP_238235 804 88265
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.2 79.4 N.A. N.A. 40.6 20.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 51.1 82.9 N.A. N.A. 52.7 26.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 60 6.6 N.A. N.A. 60 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 60 6.6 N.A. N.A. 66.6 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 20 0 0 0 20 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % E
% Phe: 20 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % F
% Gly: 0 60 20 0 60 0 40 0 60 0 0 20 20 20 20 % G
% His: 20 0 0 40 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 40 0 0 20 0 0 0 80 0 0 0 0 0 % Q
% Arg: 0 0 20 0 0 0 20 0 0 0 0 0 20 20 20 % R
% Ser: 20 0 0 20 20 60 0 60 20 0 60 60 40 20 20 % S
% Thr: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 % T
% Val: 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _