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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM133B
All Species:
13.33
Human Site:
S194
Identified Species:
32.59
UniProt:
Q5BKY9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5BKY9
NP_001035146.1
247
28385
S194
D
K
P
L
S
S
E
S
L
S
E
S
E
Y
I
Chimpanzee
Pan troglodytes
XP_519200
223
25539
E171
S
K
D
G
T
E
K
E
K
D
I
K
G
L
S
Rhesus Macaque
Macaca mulatta
XP_001100396
237
27161
S184
D
K
P
L
S
S
E
S
L
S
E
S
E
Y
I
Dog
Lupus familis
XP_852344
247
28388
S194
D
K
P
L
S
S
E
S
L
S
E
S
D
Y
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CVI2
245
27934
E192
E
D
K
P
L
S
S
E
S
L
S
E
S
D
C
Rat
Rattus norvegicus
Q505I5
245
28015
E192
E
D
K
P
L
S
S
E
S
L
S
E
S
D
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520774
262
28329
I179
V
H
R
V
S
I
V
I
S
M
G
G
E
A
F
Chicken
Gallus gallus
Q5ZLM8
250
28336
S197
D
G
P
L
S
S
E
S
L
S
G
P
D
Q
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1A5I1
259
29813
S205
E
R
S
Q
S
E
S
S
D
E
S
D
V
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793119
179
21138
N127
Q
R
K
R
R
K
K
N
K
K
E
K
K
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.8
95.5
96.7
N.A.
87.4
87
N.A.
50.3
78.4
N.A.
59
N.A.
N.A.
N.A.
N.A.
36.4
Protein Similarity:
100
89.8
95.9
97.9
N.A.
93.1
93.5
N.A.
62.5
86.8
N.A.
75.6
N.A.
N.A.
N.A.
N.A.
57.4
P-Site Identity:
100
6.6
100
93.3
N.A.
6.6
6.6
N.A.
13.3
60
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
100
100
N.A.
13.3
13.3
N.A.
20
66.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% C
% Asp:
40
20
10
0
0
0
0
0
10
10
0
10
20
30
0
% D
% Glu:
30
0
0
0
0
20
40
30
0
10
40
20
30
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
10
0
10
0
0
0
0
0
0
20
10
10
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
10
0
0
10
0
0
0
30
% I
% Lys:
0
40
30
0
0
10
20
0
20
10
0
20
10
10
10
% K
% Leu:
0
0
0
40
20
0
0
0
40
20
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
40
20
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
10
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
20
10
10
10
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
10
0
10
0
60
60
30
50
30
40
30
30
20
0
10
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% T
% Val:
10
0
0
10
0
0
10
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _