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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUNDC3A
All Species:
10.3
Human Site:
Y248
Identified Species:
25.19
UniProt:
Q59EK9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q59EK9
NP_001138297.1
446
49747
Y248
V
T
D
E
D
S
W
Y
S
K
W
H
K
M
E
Chimpanzee
Pan troglodytes
XP_001140468
454
50428
Y256
V
T
D
E
D
S
W
Y
S
K
W
H
K
M
E
Rhesus Macaque
Macaca mulatta
XP_001100710
483
54413
I278
K
R
E
L
E
G
V
I
L
E
L
Q
E
Q
L
Dog
Lupus familis
XP_537621
371
41195
S201
P
Y
L
K
F
T
Q
S
Y
D
Y
L
T
D
E
Cat
Felis silvestris
Mouse
Mus musculus
O08576
446
50000
Y248
V
T
D
E
D
S
W
Y
N
K
W
H
K
M
E
Rat
Rattus norvegicus
Q3B7K9
403
44774
V233
E
G
S
T
P
E
N
V
G
P
P
L
I
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508997
456
50767
E284
G
S
E
S
S
T
P
E
N
I
G
P
P
L
L
Chicken
Gallus gallus
NP_001026143
313
35560
F143
I
S
T
A
L
R
D
F
K
T
T
R
R
F
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A7YDW0
428
48457
N254
E
Q
R
F
K
I
V
N
A
Q
K
G
Y
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785586
443
49510
L249
A
N
Q
K
E
Q
H
L
I
E
S
R
K
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
68.3
81.8
N.A.
96.4
51.7
N.A.
50.4
43.9
N.A.
70.1
N.A.
N.A.
N.A.
N.A.
27.5
Protein Similarity:
100
79.3
72.4
82.7
N.A.
97.5
67.2
N.A.
64.9
55.3
N.A.
81.3
N.A.
N.A.
N.A.
N.A.
50.2
P-Site Identity:
100
100
0
6.6
N.A.
93.3
0
N.A.
0
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
26.6
26.6
N.A.
100
13.3
N.A.
33.3
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
30
0
30
0
10
0
0
10
0
0
0
10
10
% D
% Glu:
20
0
20
30
20
10
0
10
0
20
0
0
10
0
50
% E
% Phe:
0
0
0
10
10
0
0
10
0
0
0
0
0
10
0
% F
% Gly:
10
10
0
0
0
10
0
0
10
0
10
10
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
30
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
10
10
10
0
0
10
0
10
% I
% Lys:
10
0
0
20
10
0
0
0
10
30
10
0
40
10
0
% K
% Leu:
0
0
10
10
10
0
0
10
10
0
10
20
0
30
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% M
% Asn:
0
10
0
0
0
0
10
10
20
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
10
0
10
0
0
10
10
10
10
0
0
% P
% Gln:
0
10
10
0
0
10
10
0
0
10
0
10
0
10
0
% Q
% Arg:
0
10
10
0
0
10
0
0
0
0
0
20
10
0
0
% R
% Ser:
0
20
10
10
10
30
0
10
20
0
10
0
0
0
0
% S
% Thr:
0
30
10
10
0
20
0
0
0
10
10
0
10
0
0
% T
% Val:
30
0
0
0
0
0
20
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
30
0
0
0
30
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
30
10
0
10
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _