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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RUNDC3A All Species: 22.12
Human Site: S425 Identified Species: 54.07
UniProt: Q59EK9 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q59EK9 NP_001138297.1 446 49747 S425 P S C K S L A S F K S N E C L
Chimpanzee Pan troglodytes XP_001140468 454 50428 S433 P S C K S L A S F K S N E C L
Rhesus Macaque Macaca mulatta XP_001100710 483 54413 S462 P S C K S L A S F K S N E C L
Dog Lupus familis XP_537621 371 41195 F351 S C K S L A S F K S N E C L V
Cat Felis silvestris
Mouse Mus musculus O08576 446 50000 S425 P S C K S L A S F K S N E C L
Rat Rattus norvegicus Q3B7K9 403 44774 K383 Y K S L T S L K S N D C L A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508997 456 50767 S434 A S Y K S L T S P K S T D Y L
Chicken Gallus gallus NP_001026143 313 35560 L293 Q R I E D M D L A H K M E K E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A7YDW0 428 48457 S407 P S C K S L P S L R S T E C L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785586 443 49510 S402 L S A M S V R S N E T N S S G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74 68.3 81.8 N.A. 96.4 51.7 N.A. 50.4 43.9 N.A. 70.1 N.A. N.A. N.A. N.A. 27.5
Protein Similarity: 100 79.3 72.4 82.7 N.A. 97.5 67.2 N.A. 64.9 55.3 N.A. 81.3 N.A. N.A. N.A. N.A. 50.2
P-Site Identity: 100 100 100 0 N.A. 100 0 N.A. 53.3 6.6 N.A. 73.3 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 100 20 N.A. 100 6.6 N.A. 60 20 N.A. 80 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 10 40 0 10 0 0 0 0 10 0 % A
% Cys: 0 10 50 0 0 0 0 0 0 0 0 10 10 50 0 % C
% Asp: 0 0 0 0 10 0 10 0 0 0 10 0 10 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 10 0 10 60 0 10 % E
% Phe: 0 0 0 0 0 0 0 10 40 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 10 60 0 0 0 10 10 50 10 0 0 10 0 % K
% Leu: 10 0 0 10 10 60 10 10 10 0 0 0 10 10 60 % L
% Met: 0 0 0 10 0 10 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 10 10 50 0 0 0 % N
% Pro: 50 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 0 0 0 10 0 0 10 0 0 0 0 0 % R
% Ser: 10 70 10 10 70 10 10 70 10 10 60 0 10 10 10 % S
% Thr: 0 0 0 0 10 0 10 0 0 0 10 20 0 0 0 % T
% Val: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _