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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUNDC3A
All Species:
23.03
Human Site:
S422
Identified Species:
56.3
UniProt:
Q59EK9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q59EK9
NP_001138297.1
446
49747
S422
A
S
I
P
S
C
K
S
L
A
S
F
K
S
N
Chimpanzee
Pan troglodytes
XP_001140468
454
50428
S430
A
S
I
P
S
C
K
S
L
A
S
F
K
S
N
Rhesus Macaque
Macaca mulatta
XP_001100710
483
54413
S459
A
S
I
P
S
C
K
S
L
A
S
F
K
S
N
Dog
Lupus familis
XP_537621
371
41195
L348
S
I
P
S
C
K
S
L
A
S
F
K
S
N
E
Cat
Felis silvestris
Mouse
Mus musculus
O08576
446
50000
S422
A
S
I
P
S
C
K
S
L
A
S
F
K
S
N
Rat
Rattus norvegicus
Q3B7K9
403
44774
T380
V
A
S
Y
K
S
L
T
S
L
K
S
N
D
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508997
456
50767
S431
T
S
V
A
S
Y
K
S
L
T
S
P
K
S
T
Chicken
Gallus gallus
NP_001026143
313
35560
D290
L
L
L
Q
R
I
E
D
M
D
L
A
H
K
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A7YDW0
428
48457
S404
S
S
L
P
S
C
K
S
L
P
S
L
R
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785586
443
49510
S399
T
S
Q
L
S
A
M
S
V
R
S
N
E
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
68.3
81.8
N.A.
96.4
51.7
N.A.
50.4
43.9
N.A.
70.1
N.A.
N.A.
N.A.
N.A.
27.5
Protein Similarity:
100
79.3
72.4
82.7
N.A.
97.5
67.2
N.A.
64.9
55.3
N.A.
81.3
N.A.
N.A.
N.A.
N.A.
50.2
P-Site Identity:
100
100
100
0
N.A.
100
0
N.A.
53.3
0
N.A.
60
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
20
N.A.
100
13.3
N.A.
60
20
N.A.
80
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
10
0
10
0
10
0
0
10
40
0
10
0
0
0
% A
% Cys:
0
0
0
0
10
50
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
10
0
10
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
40
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
40
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
10
60
0
0
0
10
10
50
10
0
% K
% Leu:
10
10
20
10
0
0
10
10
60
10
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
10
10
50
% N
% Pro:
0
0
10
50
0
0
0
0
0
10
0
10
0
0
0
% P
% Gln:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
10
0
0
10
0
0
% R
% Ser:
20
70
10
10
70
10
10
70
10
10
70
10
10
60
0
% S
% Thr:
20
0
0
0
0
0
0
10
0
10
0
0
0
10
20
% T
% Val:
10
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _