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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUNDC3A
All Species:
10.61
Human Site:
S139
Identified Species:
25.93
UniProt:
Q59EK9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q59EK9
NP_001138297.1
446
49747
S139
A
L
M
E
K
R
M
S
E
Y
I
T
T
A
L
Chimpanzee
Pan troglodytes
XP_001140468
454
50428
S147
A
L
M
E
K
R
M
S
E
Y
I
T
T
A
L
Rhesus Macaque
Macaca mulatta
XP_001100710
483
54413
I169
D
G
K
T
P
V
V
I
D
Y
T
P
Y
L
K
Dog
Lupus familis
XP_537621
371
41195
C92
W
D
Y
I
R
L
A
C
S
K
V
P
N
N
C
Cat
Felis silvestris
Mouse
Mus musculus
O08576
446
50000
S139
A
L
M
E
K
R
M
S
E
Y
I
T
T
A
L
Rat
Rattus norvegicus
Q3B7K9
403
44774
W124
S
R
A
K
G
R
A
W
I
R
V
A
L
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508997
456
50767
R175
S
S
S
R
A
K
G
R
A
W
I
R
V
A
L
Chicken
Gallus gallus
NP_001026143
313
35560
C34
R
R
N
L
I
T
V
C
R
F
S
V
K
T
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A7YDW0
428
48457
T145
A
L
R
D
S
R
T
T
R
R
F
Y
D
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785586
443
49510
F140
A
F
Y
G
E
G
A
F
L
R
S
E
E
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
68.3
81.8
N.A.
96.4
51.7
N.A.
50.4
43.9
N.A.
70.1
N.A.
N.A.
N.A.
N.A.
27.5
Protein Similarity:
100
79.3
72.4
82.7
N.A.
97.5
67.2
N.A.
64.9
55.3
N.A.
81.3
N.A.
N.A.
N.A.
N.A.
50.2
P-Site Identity:
100
100
6.6
0
N.A.
100
6.6
N.A.
20
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
20
13.3
N.A.
100
26.6
N.A.
40
20
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
10
0
10
0
30
0
10
0
0
10
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
10
% C
% Asp:
10
10
0
10
0
0
0
0
10
0
0
0
10
0
0
% D
% Glu:
0
0
0
30
10
0
0
0
30
0
0
10
10
10
10
% E
% Phe:
0
10
0
0
0
0
0
10
0
10
10
0
0
0
0
% F
% Gly:
0
10
0
10
10
10
10
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
10
0
0
10
10
0
40
0
0
0
0
% I
% Lys:
0
0
10
10
30
10
0
0
0
10
0
0
10
0
10
% K
% Leu:
0
40
0
10
0
10
0
0
10
0
0
0
10
10
60
% L
% Met:
0
0
30
0
0
0
30
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
10
10
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
20
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
20
10
10
10
50
0
10
20
30
0
10
0
0
0
% R
% Ser:
20
10
10
0
10
0
0
30
10
0
20
0
0
0
0
% S
% Thr:
0
0
0
10
0
10
10
10
0
0
10
30
30
10
0
% T
% Val:
0
0
0
0
0
10
20
0
0
0
20
10
10
0
0
% V
% Trp:
10
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% W
% Tyr:
0
0
20
0
0
0
0
0
0
40
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _