KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EAPP
All Species:
14.85
Human Site:
S223
Identified Species:
25.13
UniProt:
Q56P03
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q56P03
NP_060923.2
285
32734
S223
E
V
L
R
Y
K
A
S
E
N
R
K
K
R
R
Chimpanzee
Pan troglodytes
XP_509897
285
32735
S223
E
V
L
R
Y
K
A
S
E
N
R
K
K
R
R
Rhesus Macaque
Macaca mulatta
XP_001104634
296
33316
S234
E
V
L
R
Y
K
A
S
E
N
R
K
K
R
R
Dog
Lupus familis
XP_850430
286
32978
P224
E
V
L
R
Y
K
I
P
E
N
R
K
K
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5BU09
281
32475
Y219
N
R
E
E
V
L
R
Y
K
N
P
E
N
R
R
Rat
Rattus norvegicus
NP_001128459
280
32140
K219
R
E
E
V
L
R
Y
K
N
S
D
N
R
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512221
286
33024
P224
E
I
L
R
Y
R
G
P
V
N
R
K
K
R
R
Chicken
Gallus gallus
XP_421235
287
33535
K225
V
N
K
E
E
I
L
K
Y
R
K
K
V
K
K
Frog
Xenopus laevis
NP_001085682
293
33892
Q232
E
L
L
R
F
P
V
Q
S
S
A
K
N
K
R
Zebra Danio
Brachydanio rerio
NP_956078
307
34683
I231
E
V
L
R
Y
K
T
I
N
K
R
K
Q
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_498165
467
53727
I405
L
D
G
E
K
M
A
I
E
K
T
G
K
D
R
Sea Urchin
Strong. purpuratus
XP_001197735
355
39844
S287
E
Q
L
R
Y
P
E
S
K
N
K
K
K
K
W
Poplar Tree
Populus trichocarpa
XP_002307158
149
16865
K88
N
C
K
V
D
S
N
K
V
Q
H
S
R
Q
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196449
150
17037
T88
N
C
K
V
G
T
D
T
V
L
Q
Q
N
T
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
88.1
89.5
N.A.
87.3
87.7
N.A.
74.4
68.9
63.4
61.5
N.A.
N.A.
N.A.
23.9
41.6
Protein Similarity:
100
99.6
89.8
93.3
N.A.
91.2
91.9
N.A.
82.1
82.2
77.4
73.9
N.A.
N.A.
N.A.
37.2
59.1
P-Site Identity:
100
100
100
86.6
N.A.
20
0
N.A.
66.6
6.6
33.3
60
N.A.
N.A.
N.A.
26.6
53.3
P-Site Similarity:
100
100
100
86.6
N.A.
33.3
33.3
N.A.
80
26.6
60
66.6
N.A.
N.A.
N.A.
26.6
73.3
Percent
Protein Identity:
28.4
N.A.
N.A.
27.7
N.A.
N.A.
Protein Similarity:
40
N.A.
N.A.
40.3
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
29
0
0
0
8
0
0
0
0
% A
% Cys:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
8
0
0
0
8
0
0
8
0
% D
% Glu:
58
8
15
22
8
0
8
0
36
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
8
0
8
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
8
15
0
0
0
0
0
0
0
% I
% Lys:
0
0
22
0
8
36
0
22
15
15
15
65
50
29
22
% K
% Leu:
8
8
58
0
8
8
8
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
22
8
0
0
0
0
8
0
15
50
0
8
22
0
0
% N
% Pro:
0
0
0
0
0
15
0
15
0
0
8
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
8
0
8
8
8
8
8
0
% Q
% Arg:
8
8
0
58
0
15
8
0
0
8
43
0
15
43
65
% R
% Ser:
0
0
0
0
0
8
0
29
8
15
0
8
0
8
0
% S
% Thr:
0
0
0
0
0
8
8
8
0
0
8
0
0
8
0
% T
% Val:
8
36
0
22
8
0
8
0
22
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
50
0
8
8
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _