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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EAPP
All Species:
22.73
Human Site:
S109
Identified Species:
38.46
UniProt:
Q56P03
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q56P03
NP_060923.2
285
32734
S109
Y
D
D
I
Y
F
D
S
D
S
E
D
E
D
R
Chimpanzee
Pan troglodytes
XP_509897
285
32735
S109
Y
D
D
I
Y
F
D
S
D
S
E
D
E
D
R
Rhesus Macaque
Macaca mulatta
XP_001104634
296
33316
S120
Y
D
D
I
Y
F
D
S
D
S
E
D
E
D
K
Dog
Lupus familis
XP_850430
286
32978
S109
Y
D
D
I
Y
F
D
S
D
S
E
D
E
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5BU09
281
32475
S109
Y
D
E
I
Y
F
D
S
D
S
E
D
E
D
K
Rat
Rattus norvegicus
NP_001128459
280
32140
D109
D
A
V
Y
F
D
S
D
S
E
D
E
D
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512221
286
33024
S109
Y
D
D
I
Y
F
D
S
D
S
E
D
E
E
K
Chicken
Gallus gallus
XP_421235
287
33535
D109
Y
Y
D
D
I
Y
F
D
S
D
S
E
D
E
D
Frog
Xenopus laevis
NP_001085682
293
33892
F110
Q
F
Y
D
D
V
Y
F
D
S
D
S
D
E
E
Zebra Danio
Brachydanio rerio
NP_956078
307
34683
D112
E
Y
D
S
I
Y
F
D
S
D
S
D
E
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_498165
467
53727
L196
K
S
G
Q
A
V
K
L
V
Y
S
C
K
N
G
Sea Urchin
Strong. purpuratus
XP_001197735
355
39844
G116
A
A
S
G
G
L
P
G
S
S
S
E
Q
Q
C
Poplar Tree
Populus trichocarpa
XP_002307158
149
16865
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196449
150
17037
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
88.1
89.5
N.A.
87.3
87.7
N.A.
74.4
68.9
63.4
61.5
N.A.
N.A.
N.A.
23.9
41.6
Protein Similarity:
100
99.6
89.8
93.3
N.A.
91.2
91.9
N.A.
82.1
82.2
77.4
73.9
N.A.
N.A.
N.A.
37.2
59.1
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
0
N.A.
86.6
13.3
13.3
26.6
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
100
40
33.3
33.3
N.A.
N.A.
N.A.
13.3
20
Percent
Protein Identity:
28.4
N.A.
N.A.
27.7
N.A.
N.A.
Protein Similarity:
40
N.A.
N.A.
40.3
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
0
8
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% C
% Asp:
8
43
50
15
8
8
43
22
50
15
15
50
22
43
8
% D
% Glu:
8
0
8
0
0
0
0
0
0
8
43
22
50
22
8
% E
% Phe:
0
8
0
0
8
43
15
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
8
0
0
8
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
43
15
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
8
0
0
0
0
0
8
8
29
% K
% Leu:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
8
0
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% R
% Ser:
0
8
8
8
0
0
8
43
29
58
29
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
15
0
0
8
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
50
15
8
8
43
15
8
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _