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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYCRL
All Species:
48.18
Human Site:
S106
Identified Species:
75.71
UniProt:
Q53H96
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53H96
NP_075566.2
274
28649
S106
V
S
V
A
A
G
V
S
L
S
T
L
E
E
L
Chimpanzee
Pan troglodytes
XP_528256
274
28645
S106
V
S
V
A
A
G
V
S
L
S
T
L
E
E
L
Rhesus Macaque
Macaca mulatta
XP_001097787
532
55678
S364
V
S
V
A
A
G
V
S
L
S
T
L
E
E
L
Dog
Lupus familis
XP_539200
288
29923
S120
V
S
V
A
A
G
V
S
L
S
T
L
E
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCC4
274
28703
S106
V
S
V
A
A
G
I
S
L
S
T
M
E
G
L
Rat
Rattus norvegicus
Q5PQJ6
274
28860
S106
V
S
V
A
A
G
I
S
L
S
S
M
E
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518843
344
36720
S176
V
S
L
A
A
G
V
S
L
Q
I
L
E
E
L
Chicken
Gallus gallus
XP_418406
278
29308
T110
I
S
L
A
A
G
V
T
L
Q
K
L
Q
R
L
Frog
Xenopus laevis
A1L2Q8
274
28856
T106
I
S
M
A
A
G
V
T
L
E
T
L
E
K
N
Zebra Danio
Brachydanio rerio
Q5SPD7
288
29903
T116
V
S
M
A
A
G
I
T
I
A
T
L
E
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20848
299
32038
P114
I
S
V
M
A
G
V
P
L
K
V
L
N
A
K
Sea Urchin
Strong. purpuratus
XP_788839
276
28973
S101
I
S
L
A
A
G
I
S
L
D
F
I
E
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P54904
276
28606
K109
V
S
V
A
A
G
I
K
L
N
D
L
Q
E
W
Baker's Yeast
Sacchar. cerevisiae
P32263
286
30113
T119
I
S
L
A
A
G
W
T
I
D
Q
L
S
Q
Y
Red Bread Mold
Neurospora crassa
Q12641
332
34196
T146
I
S
I
C
A
G
V
T
V
P
D
L
E
R
V
Conservation
Percent
Protein Identity:
100
99.6
50.1
82.9
N.A.
82.1
82.4
N.A.
59
59.3
58
52.7
N.A.
N.A.
N.A.
31.7
44.5
Protein Similarity:
100
99.6
51.1
88.1
N.A.
90.5
90.1
N.A.
68.9
72.3
77.7
72.2
N.A.
N.A.
N.A.
50.1
65.9
P-Site Identity:
100
100
100
100
N.A.
80
80
N.A.
80
53.3
60
66.6
N.A.
N.A.
N.A.
46.6
46.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
86.6
80
86.6
100
N.A.
N.A.
N.A.
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.1
30
30.4
Protein Similarity:
N.A.
N.A.
N.A.
59
47.9
46.6
P-Site Identity:
N.A.
N.A.
N.A.
60
33.3
40
P-Site Similarity:
N.A.
N.A.
N.A.
80
66.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
87
100
0
0
0
0
7
0
0
0
7
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
14
14
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
7
0
0
74
54
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
0
100
0
0
0
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
40
0
7
0
0
0
34
0
14
0
7
7
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
7
0
7
7
0
0
7
7
% K
% Leu:
0
0
27
0
0
0
0
0
80
0
0
80
0
0
60
% L
% Met:
0
0
14
7
0
0
0
0
0
0
0
14
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
0
0
7
7
14
% N
% Pro:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
14
7
0
14
7
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% R
% Ser:
0
100
0
0
0
0
0
54
0
40
7
0
7
0
0
% S
% Thr:
0
0
0
0
0
0
0
34
0
0
47
0
0
0
0
% T
% Val:
60
0
54
0
0
0
60
0
7
0
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _