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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP39
All Species:
23.94
Human Site:
Y252
Identified Species:
40.51
UniProt:
Q53GS9
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53GS9
NP_006581.2
565
65381
Y252
N
V
P
P
L
R
N
Y
F
L
E
E
D
N
Y
Chimpanzee
Pan troglodytes
XP_515591
565
65314
Y252
N
V
P
P
L
R
N
Y
F
L
E
E
D
N
Y
Rhesus Macaque
Macaca mulatta
XP_001089375
565
65373
Y252
N
V
P
P
L
R
N
Y
F
L
E
E
D
N
Y
Dog
Lupus familis
XP_532977
561
64749
Y248
N
V
P
P
L
R
N
Y
F
L
E
E
D
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q3TIX9
564
65128
Y251
N
V
P
P
L
R
N
Y
F
L
E
E
D
N
Y
Rat
Rattus norvegicus
NP_001100067
568
65325
Y251
N
V
P
P
L
R
N
Y
F
L
E
E
D
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518784
529
60631
F254
K
L
W
N
P
R
N
F
K
A
H
V
S
P
H
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001073539
497
57657
A223
W
N
P
R
N
F
K
A
H
V
S
P
H
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573334
494
57485
N220
E
L
M
R
K
M
W
N
P
R
N
F
K
S
H
Honey Bee
Apis mellifera
XP_394503
491
57190
L217
L
V
Q
R
F
G
E
L
M
R
K
L
W
N
P
Nematode Worm
Caenorhab. elegans
NP_494298
602
70982
W283
A
V
R
P
L
R
N
W
F
L
K
E
S
N
Y
Sea Urchin
Strong. purpuratus
XP_001178710
517
59237
I243
P
H
E
M
L
Q
A
I
V
L
C
S
K
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C585
871
98152
T287
G
L
Q
N
L
G
N
T
C
F
M
N
S
S
L
Baker's Yeast
Sacchar. cerevisiae
P43589
448
52148
V174
L
I
S
H
M
V
P
V
R
D
H
F
L
L
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
98
N.A.
97.3
94.1
N.A.
86
N.A.
N.A.
77.3
N.A.
55.5
59.1
53.9
61.5
Protein Similarity:
100
99.8
99.4
98
N.A.
98.2
95.5
N.A.
88.5
N.A.
N.A.
81
N.A.
69
70.6
69.9
73.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
N.A.
N.A.
6.6
N.A.
0
13.3
66.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
N.A.
N.A.
13.3
N.A.
20
20
80
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
27
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.1
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
8
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
0
43
0
0
% D
% Glu:
8
0
8
0
0
0
8
0
0
0
43
50
0
8
0
% E
% Phe:
0
0
0
0
8
8
0
8
50
8
0
15
0
0
0
% F
% Gly:
8
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
8
0
0
0
0
8
0
15
0
8
0
15
% H
% Ile:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
8
0
8
0
8
0
15
0
15
8
0
% K
% Leu:
15
22
0
0
65
0
0
8
0
58
0
8
8
8
8
% L
% Met:
0
0
8
8
8
8
0
0
8
0
8
0
0
0
8
% M
% Asn:
43
8
0
15
8
0
65
8
0
0
8
8
0
58
8
% N
% Pro:
8
0
50
50
8
0
8
0
8
0
0
8
0
8
8
% P
% Gln:
0
0
15
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
22
0
58
0
0
8
15
0
0
0
0
8
% R
% Ser:
0
0
8
0
0
0
0
0
0
0
8
8
22
15
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
58
0
0
0
8
0
8
8
8
0
8
0
0
0
% V
% Trp:
8
0
8
0
0
0
8
8
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
43
0
0
0
0
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _