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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP39 All Species: 26.36
Human Site: Y215 Identified Species: 44.62
UniProt: Q53GS9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53GS9 NP_006581.2 565 65381 Y215 Q A K L S R A Y D G T T Y L P
Chimpanzee Pan troglodytes XP_515591 565 65314 Y215 Q A K L S R A Y D G T T Y L P
Rhesus Macaque Macaca mulatta XP_001089375 565 65373 Y215 Q A K L S R A Y D G T T Y L P
Dog Lupus familis XP_532977 561 64749 Y211 Q A K L S R A Y D G T T Y L P
Cat Felis silvestris
Mouse Mus musculus Q3TIX9 564 65128 Y214 Q A K L S R A Y D G T T Y L P
Rat Rattus norvegicus NP_001100067 568 65325 Y214 Q A K L S R A Y D G T T Y L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518784 529 60631 F217 V P P L R N Y F L E E E N Y K
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001073539 497 57657 E186 P L R N Y F L E E E N Y R G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573334 494 57485 L183 A L S H V G P L R D Y F L Q K
Honey Bee Apis mellifera XP_394503 491 57190 L180 C N V I L Q A L S H V T P L R
Nematode Worm Caenorhab. elegans NP_494298 602 70982 Y246 Q S K M V R A Y D D S T Y F P
Sea Urchin Strong. purpuratus XP_001178710 517 59237 P206 Y G D I K L P P G N I M S I L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C585 871 98152 M250 T N G I T N G M N G G T V F R
Baker's Yeast Sacchar. cerevisiae P43589 448 52148 C137 L E D F P R Q C F D L S N R T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.4 98 N.A. 97.3 94.1 N.A. 86 N.A. N.A. 77.3 N.A. 55.5 59.1 53.9 61.5
Protein Similarity: 100 99.8 99.4 98 N.A. 98.2 95.5 N.A. 88.5 N.A. N.A. 81 N.A. 69 70.6 69.9 73.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 N.A. N.A. 0 N.A. 0 20 60 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 N.A. N.A. 13.3 N.A. 0 33.3 80 13.3
Percent
Protein Identity: N.A. N.A. N.A. 20.5 27 N.A.
Protein Similarity: N.A. N.A. N.A. 36.1 45.8 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 43 0 0 0 0 58 0 0 0 0 0 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 15 0 0 0 0 0 50 22 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 8 8 15 8 8 0 0 0 % E
% Phe: 0 0 0 8 0 8 0 8 8 0 0 8 0 15 0 % F
% Gly: 0 8 8 0 0 8 8 0 8 50 8 0 0 8 0 % G
% His: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 22 0 0 0 0 0 0 8 0 0 8 8 % I
% Lys: 0 0 50 0 8 0 0 0 0 0 0 0 0 0 15 % K
% Leu: 8 15 0 50 8 8 8 15 8 0 8 0 8 50 8 % L
% Met: 0 0 0 8 0 0 0 8 0 0 0 8 0 0 0 % M
% Asn: 0 15 0 8 0 15 0 0 8 8 8 0 15 0 0 % N
% Pro: 8 8 8 0 8 0 15 8 0 0 0 0 8 0 50 % P
% Gln: 50 0 0 0 0 8 8 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 8 0 8 58 0 0 8 0 0 0 8 8 15 % R
% Ser: 0 8 8 0 43 0 0 0 8 0 8 8 8 0 0 % S
% Thr: 8 0 0 0 8 0 0 0 0 0 43 65 0 0 8 % T
% Val: 8 0 8 0 15 0 0 0 0 0 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 8 0 8 50 0 0 8 8 50 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _