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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP39
All Species:
7.88
Human Site:
S58
Identified Species:
13.33
UniProt:
Q53GS9
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53GS9
NP_006581.2
565
65381
S58
K
R
E
F
E
P
A
S
A
R
E
A
P
A
S
Chimpanzee
Pan troglodytes
XP_515591
565
65314
S58
K
R
E
V
E
P
A
S
A
R
E
A
P
A
S
Rhesus Macaque
Macaca mulatta
XP_001089375
565
65373
S58
K
R
E
V
E
P
A
S
V
R
E
A
Q
A
S
Dog
Lupus familis
XP_532977
561
64749
R56
E
V
E
P
V
S
A
R
E
A
P
T
P
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3TIX9
564
65128
A58
K
R
E
A
E
P
A
A
R
E
V
P
A
P
A
Rat
Rattus norvegicus
NP_001100067
568
65325
P58
K
R
E
A
E
P
T
P
R
E
V
P
A
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518784
529
60631
D60
R
V
R
H
G
R
L
D
S
E
D
R
R
S
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001073539
497
57657
R31
G
R
G
Y
V
E
D
R
R
S
R
H
C
P
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573334
494
57485
P28
P
V
E
E
D
E
T
P
S
V
F
N
P
K
Y
Honey Bee
Apis mellifera
XP_394503
491
57190
I25
Q
N
N
S
D
E
E
I
N
K
R
I
K
I
T
Nematode Worm
Caenorhab. elegans
NP_494298
602
70982
K89
T
T
P
P
A
P
E
K
P
R
Q
L
T
A
R
Sea Urchin
Strong. purpuratus
XP_001178710
517
59237
I51
S
C
P
Y
L
D
T
I
N
R
G
L
L
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C585
871
98152
C57
E
I
L
Y
T
A
S
C
G
S
S
Y
G
G
P
Baker's Yeast
Sacchar. cerevisiae
P43589
448
52148
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
98
N.A.
97.3
94.1
N.A.
86
N.A.
N.A.
77.3
N.A.
55.5
59.1
53.9
61.5
Protein Similarity:
100
99.8
99.4
98
N.A.
98.2
95.5
N.A.
88.5
N.A.
N.A.
81
N.A.
69
70.6
69.9
73.2
P-Site Identity:
100
93.3
80
20
N.A.
40
33.3
N.A.
0
N.A.
N.A.
6.6
N.A.
13.3
0
20
6.6
P-Site Similarity:
100
93.3
80
26.6
N.A.
53.3
33.3
N.A.
26.6
N.A.
N.A.
13.3
N.A.
26.6
26.6
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
27
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.1
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
8
8
36
8
15
8
0
22
15
29
8
% A
% Cys:
0
8
0
0
0
0
0
8
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
15
8
8
8
0
0
8
0
0
8
0
% D
% Glu:
15
0
50
8
36
22
15
0
8
22
22
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
8
% F
% Gly:
8
0
8
0
8
0
0
0
8
0
8
0
8
8
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
15
0
0
0
8
0
8
0
% I
% Lys:
36
0
0
0
0
0
0
8
0
8
0
0
8
8
0
% K
% Leu:
0
0
8
0
8
0
8
0
0
0
0
15
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
15
0
0
8
0
0
0
% N
% Pro:
8
0
15
15
0
43
0
15
8
0
8
15
29
22
8
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% Q
% Arg:
8
43
8
0
0
8
0
15
22
36
15
8
8
0
15
% R
% Ser:
8
0
0
8
0
8
8
22
15
15
8
0
0
8
22
% S
% Thr:
8
8
0
0
8
0
22
0
0
0
0
8
8
0
8
% T
% Val:
0
22
0
15
15
0
0
0
8
8
15
0
0
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
22
0
0
0
0
0
0
0
8
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _