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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP39
All Species:
23.94
Human Site:
S352
Identified Species:
40.51
UniProt:
Q53GS9
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53GS9
NP_006581.2
565
65381
S352
V
T
D
V
F
Q
G
S
M
R
I
F
T
K
K
Chimpanzee
Pan troglodytes
XP_515591
565
65314
S352
V
T
D
V
F
Q
G
S
M
R
I
F
T
K
K
Rhesus Macaque
Macaca mulatta
XP_001089375
565
65373
S352
V
T
D
V
F
Q
G
S
M
R
I
F
T
K
K
Dog
Lupus familis
XP_532977
561
64749
S348
V
T
D
V
F
Q
G
S
M
R
I
F
T
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3TIX9
564
65128
S351
V
N
D
V
F
Q
G
S
M
R
I
F
T
K
K
Rat
Rattus norvegicus
NP_001100067
568
65325
S351
V
N
D
V
F
Q
G
S
M
R
I
F
T
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518784
529
60631
E333
H
P
D
L
P
A
E
E
K
E
H
L
L
H
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001073539
497
57657
A302
L
P
P
E
E
K
E
A
L
L
L
K
E
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573334
494
57485
L299
R
K
M
P
P
V
E
L
D
D
A
A
K
A
Q
Honey Bee
Apis mellifera
XP_394503
491
57190
K296
H
M
R
I
Y
T
R
K
I
P
P
L
E
L
E
Nematode Worm
Caenorhab. elegans
NP_494298
602
70982
M383
S
K
T
F
R
G
R
M
R
Q
Y
S
R
R
V
Sea Urchin
Strong. purpuratus
XP_001178710
517
59237
T322
K
T
E
E
Y
K
E
T
E
Q
D
Q
P
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C585
871
98152
P403
A
K
D
G
D
G
R
P
D
A
E
V
A
D
E
Baker's Yeast
Sacchar. cerevisiae
P43589
448
52148
I253
S
S
N
D
L
K
S
I
L
N
H
S
C
K
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
98
N.A.
97.3
94.1
N.A.
86
N.A.
N.A.
77.3
N.A.
55.5
59.1
53.9
61.5
Protein Similarity:
100
99.8
99.4
98
N.A.
98.2
95.5
N.A.
88.5
N.A.
N.A.
81
N.A.
69
70.6
69.9
73.2
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
6.6
N.A.
N.A.
0
N.A.
0
0
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
N.A.
N.A.
40
N.A.
6.6
26.6
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
27
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.1
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
8
0
8
8
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
58
8
8
0
0
0
15
8
8
0
0
8
0
% D
% Glu:
0
0
8
15
8
0
29
8
8
8
8
0
15
8
15
% E
% Phe:
0
0
0
8
43
0
0
0
0
0
0
43
0
8
0
% F
% Gly:
0
0
0
8
0
15
43
0
0
0
0
0
0
0
8
% G
% His:
15
0
0
0
0
0
0
0
0
0
15
0
0
8
0
% H
% Ile:
0
0
0
8
0
0
0
8
8
0
43
0
0
0
0
% I
% Lys:
8
22
0
0
0
22
0
8
8
0
0
8
8
50
43
% K
% Leu:
8
0
0
8
8
0
0
8
15
8
8
15
8
8
8
% L
% Met:
0
8
8
0
0
0
0
8
43
0
0
0
0
0
0
% M
% Asn:
0
15
8
0
0
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
0
15
8
8
15
0
0
8
0
8
8
0
8
0
0
% P
% Gln:
0
0
0
0
0
43
0
0
0
15
0
8
0
0
8
% Q
% Arg:
8
0
8
0
8
0
22
0
8
43
0
0
8
8
0
% R
% Ser:
15
8
0
0
0
0
8
43
0
0
0
15
0
0
0
% S
% Thr:
0
36
8
0
0
8
0
8
0
0
0
0
43
0
0
% T
% Val:
43
0
0
43
0
8
0
0
0
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
15
0
0
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _