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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLE1
All Species:
26.06
Human Site:
S194
Identified Species:
57.33
UniProt:
Q53GS7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53GS7
NP_001003722.1
698
79836
S194
L
R
E
V
M
E
K
S
S
R
E
A
L
G
H
Chimpanzee
Pan troglodytes
XP_001159347
697
79620
S194
L
R
E
V
M
E
K
S
S
R
E
A
L
G
H
Rhesus Macaque
Macaca mulatta
XP_001110844
698
79589
S194
L
R
E
V
M
E
K
S
S
R
E
A
L
G
H
Dog
Lupus familis
XP_537825
623
70823
S194
L
R
E
V
M
E
K
S
S
R
E
A
L
G
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8R322
699
79556
S196
L
Q
E
V
M
E
K
S
T
R
E
A
L
G
H
Rat
Rattus norvegicus
Q4KLN4
698
79473
S195
L
Q
E
V
M
E
K
S
T
R
E
A
L
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415496
726
82611
S223
L
R
E
V
M
E
K
S
L
K
E
T
Q
G
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRB1
695
79110
E217
I
R
D
T
N
E
K
E
A
Q
E
S
L
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4W1
677
77341
L207
I
A
K
I
L
L
S
L
N
P
E
T
V
K
V
Honey Bee
Apis mellifera
XP_396401
527
60485
M132
Q
I
D
E
M
H
G
M
F
K
S
E
I
D
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202839
632
72578
H184
M
R
E
K
R
L
L
H
Q
Q
E
L
Q
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.1
71.6
N.A.
83.4
84.2
N.A.
N.A.
57.5
N.A.
50
N.A.
23.7
25.7
N.A.
33.6
Protein Similarity:
100
99.4
98.2
78
N.A.
90.1
90.2
N.A.
N.A.
73.9
N.A.
69.3
N.A.
44.5
44.5
N.A.
51.1
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
66.6
N.A.
40
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
73.3
N.A.
73.3
N.A.
46.6
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
10
0
0
55
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
73
10
0
73
0
10
0
0
91
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
73
0
% G
% His:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
55
% H
% Ile:
19
10
0
10
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
10
10
0
0
73
0
0
19
0
0
0
10
0
% K
% Leu:
64
0
0
0
10
19
10
10
10
0
0
10
64
0
10
% L
% Met:
10
0
0
0
73
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
10
19
0
0
0
0
0
0
10
19
0
0
19
0
10
% Q
% Arg:
0
64
0
0
10
0
0
0
0
55
0
0
0
10
19
% R
% Ser:
0
0
0
0
0
0
10
64
37
0
10
10
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
19
0
0
19
0
0
0
% T
% Val:
0
0
0
64
0
0
0
0
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _