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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPPE1
All Species:
19.09
Human Site:
Y344
Identified Species:
38.18
UniProt:
Q53F39
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53F39
NP_075563.3
396
45141
Y344
G
S
I
T
P
T
D
Y
T
L
S
K
C
Y
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095328
396
45252
Y344
G
S
I
T
P
T
D
Y
A
L
S
K
C
Y
L
Dog
Lupus familis
XP_547678
391
44656
Y339
G
S
M
T
P
T
E
Y
A
L
A
K
C
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80XL7
396
45994
Y344
G
S
L
T
S
R
D
Y
A
L
S
K
C
Y
L
Rat
Rattus norvegicus
B1WC86
394
45635
Y342
G
S
L
T
S
R
D
Y
A
L
S
K
C
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZK82
398
45772
F346
G
S
I
T
P
T
D
F
S
L
H
K
C
F
L
Frog
Xenopus laevis
Q0IHA5
405
46737
I351
P
S
F
I
M
G
S
I
T
A
T
K
Y
S
L
Zebra Danio
Brachydanio rerio
Q566Y9
381
44050
F329
G
T
F
S
Q
S
E
F
Q
L
S
K
C
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLR9
370
43301
Y316
A
T
I
T
P
D
D
Y
V
V
S
K
C
K
M
Honey Bee
Apis mellifera
XP_625094
383
44994
L330
K
D
N
P
S
L
L
L
G
V
F
T
P
N
N
Nematode Worm
Caenorhab. elegans
Q95X35
473
54796
A358
N
N
I
A
V
C
T
A
I
I
L
V
M
I
I
Sea Urchin
Strong. purpuratus
XP_780915
393
44826
I341
P
S
L
I
L
A
S
I
S
P
T
S
I
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.6
78.5
N.A.
73.4
72.9
N.A.
N.A.
65
56.7
53.5
N.A.
39.9
42.4
25.3
44.7
Protein Similarity:
100
N.A.
96.7
85.6
N.A.
83
81
N.A.
N.A.
75.8
70.3
71.4
N.A.
56.5
62.1
43.1
59.8
P-Site Identity:
100
N.A.
93.3
73.3
N.A.
73.3
73.3
N.A.
N.A.
73.3
26.6
40
N.A.
53.3
0
6.6
6.6
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
80
80
N.A.
N.A.
93.3
33.3
80
N.A.
73.3
6.6
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
9
0
9
34
9
9
0
0
9
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
67
0
0
% C
% Asp:
0
9
0
0
0
9
50
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
17
0
0
0
0
17
0
0
9
0
0
17
0
% F
% Gly:
59
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
42
17
0
0
0
17
9
9
0
0
9
9
17
% I
% Lys:
9
0
0
0
0
0
0
0
0
0
0
75
0
9
0
% K
% Leu:
0
0
25
0
9
9
9
9
0
59
9
0
0
0
67
% L
% Met:
0
0
9
0
9
0
0
0
0
0
0
0
9
0
9
% M
% Asn:
9
9
9
0
0
0
0
0
0
0
0
0
0
9
9
% N
% Pro:
17
0
0
9
42
0
0
0
0
9
0
0
9
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
67
0
9
25
9
17
0
17
0
50
9
0
9
0
% S
% Thr:
0
17
0
59
0
34
9
0
17
0
17
9
0
0
0
% T
% Val:
0
0
0
0
9
0
0
0
9
17
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
9
42
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _