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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPPE1
All Species:
22.12
Human Site:
Y164
Identified Species:
44.24
UniProt:
Q53F39
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53F39
NP_075563.3
396
45141
Y164
N
H
D
I
G
F
H
Y
E
M
N
T
Y
K
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095328
396
45252
Y164
N
H
D
I
G
F
H
Y
E
M
N
T
Y
K
V
Dog
Lupus familis
XP_547678
391
44656
Y159
N
H
D
I
G
F
H
Y
Q
M
S
T
Y
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q80XL7
396
45994
Y162
N
H
D
V
G
F
H
Y
Q
M
S
K
Y
R
I
Rat
Rattus norvegicus
B1WC86
394
45635
Y161
N
H
D
I
G
F
H
Y
Q
M
S
K
Y
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZK82
398
45772
M164
D
I
G
F
H
Y
E
M
T
T
Y
K
V
H
R
Frog
Xenopus laevis
Q0IHA5
405
46737
S173
D
M
T
V
Y
K
L
S
R
F
E
K
T
F
N
Zebra Danio
Brachydanio rerio
Q566Y9
381
44050
M148
D
I
G
F
H
H
E
M
T
K
Q
K
L
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLR9
370
43301
Y139
N
H
D
V
G
F
H
Y
K
M
H
P
F
F
M
Honey Bee
Apis mellifera
XP_625094
383
44994
D152
Y
V
V
A
G
N
H
D
I
G
F
H
Y
G
I
Nematode Worm
Caenorhab. elegans
Q95X35
473
54796
I141
D
L
G
F
H
Y
A
I
M
P
E
T
L
E
M
Sea Urchin
Strong. purpuratus
XP_780915
393
44826
M157
D
V
G
F
H
D
F
M
S
K
R
K
L
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.6
78.5
N.A.
73.4
72.9
N.A.
N.A.
65
56.7
53.5
N.A.
39.9
42.4
25.3
44.7
Protein Similarity:
100
N.A.
96.7
85.6
N.A.
83
81
N.A.
N.A.
75.8
70.3
71.4
N.A.
56.5
62.1
43.1
59.8
P-Site Identity:
100
N.A.
100
80
N.A.
60
66.6
N.A.
N.A.
0
0
0
N.A.
53.3
20
6.6
0
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
N.A.
13.3
13.3
13.3
N.A.
86.6
26.6
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
42
0
50
0
0
9
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
17
0
17
0
17
0
0
25
0
% E
% Phe:
0
0
0
34
0
50
9
0
0
9
9
0
9
17
0
% F
% Gly:
0
0
34
0
59
0
0
0
0
9
0
0
0
9
0
% G
% His:
0
50
0
0
34
9
59
0
0
0
9
9
0
9
0
% H
% Ile:
0
17
0
34
0
0
0
9
9
0
0
0
0
0
34
% I
% Lys:
0
0
0
0
0
9
0
0
9
17
0
50
0
25
0
% K
% Leu:
0
9
0
0
0
0
9
0
0
0
0
0
25
0
0
% L
% Met:
0
9
0
0
0
0
0
25
9
50
0
0
0
0
17
% M
% Asn:
50
0
0
0
0
9
0
0
0
0
17
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
25
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
9
0
0
17
25
% R
% Ser:
0
0
0
0
0
0
0
9
9
0
25
0
0
0
0
% S
% Thr:
0
0
9
0
0
0
0
0
17
9
0
34
9
0
0
% T
% Val:
0
17
9
25
0
0
0
0
0
0
0
0
9
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
9
17
0
50
0
0
9
0
50
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _