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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPPE1
All Species:
33.94
Human Site:
S325
Identified Species:
67.88
UniProt:
Q53F39
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53F39
NP_075563.3
396
45141
S325
E
L
S
V
P
S
F
S
W
R
N
R
N
N
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095328
396
45252
S325
E
F
S
V
P
S
F
S
W
R
N
R
N
N
P
Dog
Lupus familis
XP_547678
391
44656
S320
E
I
S
V
P
S
F
S
W
R
N
R
N
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80XL7
396
45994
S325
E
V
S
V
P
S
F
S
W
R
N
R
N
N
P
Rat
Rattus norvegicus
B1WC86
394
45635
S323
E
V
S
V
P
S
F
S
W
R
N
R
N
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZK82
398
45772
S327
E
I
S
I
P
S
F
S
W
R
N
R
N
N
P
Frog
Xenopus laevis
Q0IHA5
405
46737
S332
Q
G
K
I
P
E
I
S
V
P
S
F
S
W
R
Zebra Danio
Brachydanio rerio
Q566Y9
381
44050
S310
E
I
S
V
P
S
F
S
W
R
N
R
N
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLR9
370
43301
S297
E
Y
T
V
A
S
F
S
W
R
N
K
V
N
P
Honey Bee
Apis mellifera
XP_625094
383
44994
L311
R
I
H
R
K
D
I
L
E
F
T
I
S
S
F
Nematode Worm
Caenorhab. elegans
Q95X35
473
54796
D339
I
L
A
K
M
Y
N
D
L
I
T
P
A
P
L
Sea Urchin
Strong. purpuratus
XP_780915
393
44826
S322
Q
N
V
T
P
E
I
S
V
P
S
F
S
W
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.6
78.5
N.A.
73.4
72.9
N.A.
N.A.
65
56.7
53.5
N.A.
39.9
42.4
25.3
44.7
Protein Similarity:
100
N.A.
96.7
85.6
N.A.
83
81
N.A.
N.A.
75.8
70.3
71.4
N.A.
56.5
62.1
43.1
59.8
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
13.3
93.3
N.A.
66.6
0
6.6
13.3
P-Site Similarity:
100
N.A.
93.3
100
N.A.
100
100
N.A.
N.A.
100
40
100
N.A.
80
20
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% D
% Glu:
67
0
0
0
0
17
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
67
0
0
9
0
17
0
0
9
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
34
0
17
0
0
25
0
0
9
0
9
0
0
0
% I
% Lys:
0
0
9
9
9
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
17
0
0
0
0
0
9
9
0
0
0
0
0
9
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
9
0
0
0
67
0
59
67
0
% N
% Pro:
0
0
0
0
75
0
0
0
0
17
0
9
0
9
67
% P
% Gln:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
9
0
0
0
0
0
67
0
59
0
0
17
% R
% Ser:
0
0
59
0
0
67
0
84
0
0
17
0
25
9
0
% S
% Thr:
0
0
9
9
0
0
0
0
0
0
17
0
0
0
0
% T
% Val:
0
17
9
59
0
0
0
0
17
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
67
0
0
0
0
17
0
% W
% Tyr:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _