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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPPE1
All Species:
9.7
Human Site:
S256
Identified Species:
19.39
UniProt:
Q53F39
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53F39
NP_075563.3
396
45141
S256
H
Y
P
L
Y
R
R
S
D
A
N
C
S
G
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095328
396
45252
S256
H
Y
P
L
Y
R
R
S
D
A
N
C
S
G
D
Dog
Lupus familis
XP_547678
391
44656
S251
H
F
P
L
Y
R
S
S
D
A
N
C
S
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80XL7
396
45994
R254
L
Q
H
Y
P
L
Y
R
A
S
D
A
N
C
S
Rat
Rattus norvegicus
B1WC86
394
45635
A253
Q
H
Y
P
L
Y
R
A
S
D
A
N
C
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZK82
398
45772
R256
L
Q
H
Y
P
L
Y
R
K
S
D
A
E
C
S
Frog
Xenopus laevis
Q0IHA5
405
46737
Y265
L
L
Q
H
Y
P
L
Y
R
I
S
D
S
E
C
Zebra Danio
Brachydanio rerio
Q566Y9
381
44050
V240
Q
H
Y
P
L
Y
R
V
S
D
A
M
C
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLR9
370
43301
I231
Q
H
F
P
T
Y
R
I
S
D
T
M
C
E
E
Honey Bee
Apis mellifera
XP_625094
383
44994
F244
R
P
I
I
L
Q
H
F
P
M
Y
R
E
S
D
Nematode Worm
Caenorhab. elegans
Q95X35
473
54796
M233
H
E
I
D
L
K
E
M
Y
R
E
Q
W
D
T
Sea Urchin
Strong. purpuratus
XP_780915
393
44826
L249
P
A
S
P
P
I
L
L
Q
H
F
P
L
Y
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.6
78.5
N.A.
73.4
72.9
N.A.
N.A.
65
56.7
53.5
N.A.
39.9
42.4
25.3
44.7
Protein Similarity:
100
N.A.
96.7
85.6
N.A.
83
81
N.A.
N.A.
75.8
70.3
71.4
N.A.
56.5
62.1
43.1
59.8
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
0
6.6
N.A.
N.A.
0
13.3
6.6
N.A.
13.3
0
6.6
0
P-Site Similarity:
100
N.A.
100
93.3
N.A.
20
20
N.A.
N.A.
13.3
20
13.3
N.A.
20
20
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
9
9
25
17
17
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
25
25
17
9
% C
% Asp:
0
0
0
9
0
0
0
0
25
25
17
9
0
9
17
% D
% Glu:
0
9
0
0
0
0
9
0
0
0
9
0
17
17
25
% E
% Phe:
0
9
9
0
0
0
0
9
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
17
% G
% His:
34
25
17
9
0
0
9
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
17
9
0
9
0
9
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% K
% Leu:
25
9
0
25
34
17
17
9
0
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
9
0
9
0
17
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
25
9
9
0
0
% N
% Pro:
9
9
25
34
25
9
0
0
9
0
0
9
0
0
0
% P
% Gln:
25
17
9
0
0
9
0
0
9
0
0
9
0
0
0
% Q
% Arg:
9
0
0
0
0
25
42
17
9
9
0
9
0
0
9
% R
% Ser:
0
0
9
0
0
0
9
25
25
17
9
0
34
17
17
% S
% Thr:
0
0
0
0
9
0
0
0
0
0
9
0
0
9
9
% T
% Val:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
17
17
17
34
25
17
9
9
0
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _