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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPPE1
All Species:
30.61
Human Site:
S218
Identified Species:
61.21
UniProt:
Q53F39
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53F39
NP_075563.3
396
45141
S218
E
A
E
L
I
E
V
S
H
R
L
N
C
S
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095328
396
45252
S218
E
A
E
L
I
E
V
S
H
R
L
N
C
S
R
Dog
Lupus familis
XP_547678
391
44656
S213
E
R
E
L
I
E
I
S
H
K
L
N
C
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80XL7
396
45994
S216
E
A
E
L
R
E
I
S
R
K
L
N
C
S
Q
Rat
Rattus norvegicus
B1WC86
394
45635
S215
E
A
E
L
R
E
I
S
R
K
L
N
C
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZK82
398
45772
S218
E
A
K
L
V
A
L
S
H
R
L
N
C
S
L
Frog
Xenopus laevis
Q0IHA5
405
46737
S227
E
D
Q
L
R
R
I
S
I
K
L
N
C
S
R
Zebra Danio
Brachydanio rerio
Q566Y9
381
44050
S202
E
E
E
L
Q
K
L
S
H
A
L
N
C
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLR9
370
43301
N193
Q
A
E
D
Q
L
K
N
I
S
R
T
L
Y
C
Honey Bee
Apis mellifera
XP_625094
383
44994
E206
C
F
L
C
R
P
T
E
I
A
L
N
K
I
A
Nematode Worm
Caenorhab. elegans
Q95X35
473
54796
K195
E
L
I
L
E
K
I
K
S
R
N
P
K
N
R
Sea Urchin
Strong. purpuratus
XP_780915
393
44826
S211
Q
T
K
L
R
G
V
S
E
R
L
N
C
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.6
78.5
N.A.
73.4
72.9
N.A.
N.A.
65
56.7
53.5
N.A.
39.9
42.4
25.3
44.7
Protein Similarity:
100
N.A.
96.7
85.6
N.A.
83
81
N.A.
N.A.
75.8
70.3
71.4
N.A.
56.5
62.1
43.1
59.8
P-Site Identity:
100
N.A.
100
80
N.A.
66.6
66.6
N.A.
N.A.
66.6
53.3
60
N.A.
13.3
13.3
26.6
60
P-Site Similarity:
100
N.A.
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
86.6
73.3
73.3
N.A.
26.6
13.3
46.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
0
9
0
0
0
17
0
0
0
0
9
% A
% Cys:
9
0
0
9
0
0
0
0
0
0
0
0
75
0
9
% C
% Asp:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
75
9
59
0
9
42
0
9
9
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
42
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
25
0
42
0
25
0
0
0
0
9
9
% I
% Lys:
0
0
17
0
0
17
9
9
0
34
0
0
17
0
0
% K
% Leu:
0
9
9
84
0
9
17
0
0
0
84
0
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
9
84
0
9
0
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% P
% Gln:
17
0
9
0
17
0
0
0
0
0
0
0
0
0
17
% Q
% Arg:
0
9
0
0
42
9
0
0
17
42
9
0
0
0
50
% R
% Ser:
0
0
0
0
0
0
0
75
9
9
0
0
0
75
0
% S
% Thr:
0
9
0
0
0
0
9
0
0
0
0
9
0
0
0
% T
% Val:
0
0
0
0
9
0
25
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _