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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPPE1
All Species:
25.76
Human Site:
S185
Identified Species:
51.52
UniProt:
Q53F39
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53F39
NP_075563.3
396
45141
S185
F
S
S
E
R
L
F
S
W
K
G
I
N
F
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095328
396
45252
S185
F
S
S
E
R
L
F
S
W
K
G
I
N
F
V
Dog
Lupus familis
XP_547678
391
44656
S180
F
N
P
E
R
L
F
S
W
K
G
I
N
F
V
Cat
Felis silvestris
Mouse
Mus musculus
Q80XL7
396
45994
S183
F
G
S
E
R
L
L
S
L
K
G
V
N
F
V
Rat
Rattus norvegicus
B1WC86
394
45635
S182
F
G
S
E
R
L
F
S
L
K
G
V
N
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZK82
398
45772
T185
F
T
S
G
K
L
I
T
R
K
G
T
N
F
V
Frog
Xenopus laevis
Q0IHA5
405
46737
H194
V
S
P
K
G
I
N
H
I
L
S
S
S
F
V
Zebra Danio
Brachydanio rerio
Q566Y9
381
44050
T169
V
T
S
A
R
I
L
T
I
K
G
V
N
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLR9
370
43301
L160
L
N
N
S
S
V
N
L
Y
T
I
K
Q
I
H
Honey Bee
Apis mellifera
XP_625094
383
44994
S173
R
F
V
N
G
L
K
S
P
S
V
K
R
V
S
Nematode Worm
Caenorhab. elegans
Q95X35
473
54796
K162
R
G
L
I
D
E
M
K
I
K
K
H
R
F
V
Sea Urchin
Strong. purpuratus
XP_780915
393
44826
T178
S
S
G
V
E
V
V
T
L
K
N
N
S
F
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.6
78.5
N.A.
73.4
72.9
N.A.
N.A.
65
56.7
53.5
N.A.
39.9
42.4
25.3
44.7
Protein Similarity:
100
N.A.
96.7
85.6
N.A.
83
81
N.A.
N.A.
75.8
70.3
71.4
N.A.
56.5
62.1
43.1
59.8
P-Site Identity:
100
N.A.
100
86.6
N.A.
73.3
80
N.A.
N.A.
53.3
20
40
N.A.
0
13.3
20
26.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
80
86.6
N.A.
N.A.
73.3
40
73.3
N.A.
26.6
13.3
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
42
9
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
50
9
0
0
0
0
34
0
0
0
0
0
0
84
0
% F
% Gly:
0
25
9
9
17
0
0
0
0
0
59
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
9
% H
% Ile:
0
0
0
9
0
17
9
0
25
0
9
25
0
9
0
% I
% Lys:
0
0
0
9
9
0
9
9
0
75
9
17
0
0
0
% K
% Leu:
9
0
9
0
0
59
17
9
25
9
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
9
9
0
0
17
0
0
0
9
9
59
0
0
% N
% Pro:
0
0
17
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
17
0
0
0
50
0
0
0
9
0
0
0
17
0
0
% R
% Ser:
9
34
50
9
9
0
0
50
0
9
9
9
17
0
9
% S
% Thr:
0
17
0
0
0
0
0
25
0
9
0
9
0
0
0
% T
% Val:
17
0
9
9
0
17
9
0
0
0
9
25
0
9
75
% V
% Trp:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _