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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDCD4 All Species: 33.64
Human Site: T285 Identified Species: 74
UniProt: Q53EL6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53EL6 NP_055271.2 469 51721 T285 Y I D S Y K G T V D C V Q A R
Chimpanzee Pan troglodytes XP_001143474 469 51730 T285 Y I D S Y K G T V D C V Q A R
Rhesus Macaque Macaca mulatta XP_001086788 469 51733 T285 Y I D S Y K G T V D C V Q A R
Dog Lupus familis XP_535012 469 51702 T285 Y I D S Y K G T V D C V Q A R
Cat Felis silvestris
Mouse Mus musculus Q61823 469 51684 T285 Y I D S Y K G T V D C V Q A R
Rat Rattus norvegicus Q9JID1 469 51718 T285 Y I D S Y K G T V D C V Q A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513214 469 51772 T285 Y I D S Y K G T V D C V Q A R
Chicken Gallus gallus Q98TX3 467 51689 T283 Y I D G Y K G T V D S I Q A R
Frog Xenopus laevis NP_001080530 455 50476 I271 Y L E A Y R G I V D C V H S R
Zebra Danio Brachydanio rerio NP_945329 470 51893 V286 L D G Y K G R V D C E Y A R A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781080 464 51309 S280 F V Q Q L K G S M Q C E H G R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98 98.2 N.A. 96.5 96.5 N.A. 93.1 84.8 73.7 69.7 N.A. N.A. N.A. N.A. 47.9
Protein Similarity: 100 100 99.5 99.5 N.A. 98.5 98.7 N.A. 97.8 93.1 86.9 83.8 N.A. N.A. N.A. N.A. 66.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 80 53.3 0 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 86.6 86.6 0 N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 0 10 73 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 82 0 0 0 0 % C
% Asp: 0 10 73 0 0 0 0 0 10 82 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 10 10 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 10 0 10 91 0 0 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % H
% Ile: 0 73 0 0 0 0 0 10 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 10 82 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 10 0 0 0 0 0 10 0 0 73 0 0 % Q
% Arg: 0 0 0 0 0 10 10 0 0 0 0 0 0 10 91 % R
% Ser: 0 0 0 64 0 0 0 10 0 0 10 0 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 73 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 10 82 0 0 73 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 82 0 0 10 82 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _