KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPC2
All Species:
30.91
Human Site:
T614
Identified Species:
61.82
UniProt:
Q52LR7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q52LR7
NP_056445.3
807
91095
T614
S
Q
H
S
S
Q
Q
T
H
P
K
A
Q
G
S
Chimpanzee
Pan troglodytes
XP_526096
815
91684
T622
S
Q
H
S
S
Q
Q
T
H
P
K
A
Q
G
S
Rhesus Macaque
Macaca mulatta
XP_001118113
806
91202
T613
S
Q
H
S
S
Q
Q
T
H
P
K
A
Q
G
S
Dog
Lupus familis
XP_533350
788
88605
T595
S
Q
H
S
S
Q
Q
T
H
P
K
A
Q
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0I4
808
90941
T615
S
Q
H
S
S
Q
Q
T
H
P
K
A
Q
G
S
Rat
Rattus norvegicus
NP_001102051
808
90800
T615
S
Q
H
S
S
Q
Q
T
H
P
K
A
Q
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509590
778
87501
T585
S
Q
H
S
S
Q
P
T
H
P
Q
A
Q
G
S
Chicken
Gallus gallus
XP_422154
784
88610
R595
Q
Q
L
V
Q
M
Q
R
Q
Q
L
A
Q
L
Q
Frog
Xenopus laevis
Q66JA8
804
90630
S611
S
Q
Q
S
L
Q
Q
S
H
P
K
A
Q
G
S
Zebra Danio
Brachydanio rerio
NP_957369
751
84595
Q563
S
G
G
F
T
E
E
Q
F
Q
S
H
Q
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397232
868
96064
C678
S
N
A
V
S
T
Q
C
A
N
A
A
I
E
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192895
443
51775
E255
L
E
M
V
K
R
R
E
K
S
K
R
E
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
94.1
93.5
N.A.
96.9
96.4
N.A.
86.1
91.5
84.3
60.3
N.A.
N.A.
35.7
N.A.
31.3
Protein Similarity:
100
94.2
95.2
95
N.A.
98.1
98.1
N.A.
89.9
93.6
90.9
72.8
N.A.
N.A.
51.5
N.A.
40.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
26.6
80
13.3
N.A.
N.A.
26.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
26.6
86.6
33.3
N.A.
N.A.
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
9
0
9
84
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
9
9
9
0
0
0
0
9
9
0
% E
% Phe:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
0
0
0
0
0
0
0
0
0
67
0
% G
% His:
0
0
59
0
0
0
0
0
67
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
9
0
0
0
9
0
67
0
0
0
0
% K
% Leu:
9
0
9
0
9
0
0
0
0
0
9
0
0
9
9
% L
% Met:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
9
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
9
0
0
67
0
0
0
0
0
% P
% Gln:
9
75
9
0
9
67
75
9
9
17
9
0
84
9
17
% Q
% Arg:
0
0
0
0
0
9
9
9
0
0
0
9
0
0
0
% R
% Ser:
84
0
0
67
67
0
0
9
0
9
9
0
0
0
67
% S
% Thr:
0
0
0
0
9
9
0
59
0
0
0
0
0
0
9
% T
% Val:
0
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _