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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPC2
All Species:
1.82
Human Site:
S289
Identified Species:
3.64
UniProt:
Q52LR7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q52LR7
NP_056445.3
807
91095
S289
I
L
N
E
V
K
I
S
R
S
E
K
E
L
Y
Chimpanzee
Pan troglodytes
XP_526096
815
91684
N297
I
L
N
E
V
K
I
N
R
S
E
K
E
L
Y
Rhesus Macaque
Macaca mulatta
XP_001118113
806
91202
N288
I
L
N
E
V
K
I
N
R
S
E
K
E
L
Y
Dog
Lupus familis
XP_533350
788
88605
N270
I
L
N
E
V
K
I
N
R
S
D
K
E
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0I4
808
90941
N289
I
L
N
E
V
K
V
N
R
S
E
K
E
L
Y
Rat
Rattus norvegicus
NP_001102051
808
90800
N289
I
L
N
E
V
K
V
N
R
S
E
K
E
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509590
778
87501
Y267
N
R
P
E
K
E
I
Y
T
T
P
A
S
L
H
Chicken
Gallus gallus
XP_422154
784
88610
N289
I
L
N
E
V
K
L
N
R
P
E
K
E
M
S
Frog
Xenopus laevis
Q66JA8
804
90630
P289
I
L
N
E
I
K
I
P
K
A
D
K
E
I
Y
Zebra Danio
Brachydanio rerio
NP_957369
751
84595
L264
S
K
R
E
L
L
H
L
T
L
E
V
F
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397232
868
96064
L281
I
L
A
E
V
S
A
L
K
T
P
R
P
A
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192895
443
51775
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
94.1
93.5
N.A.
96.9
96.4
N.A.
86.1
91.5
84.3
60.3
N.A.
N.A.
35.7
N.A.
31.3
Protein Similarity:
100
94.2
95.2
95
N.A.
98.1
98.1
N.A.
89.9
93.6
90.9
72.8
N.A.
N.A.
51.5
N.A.
40.8
P-Site Identity:
100
93.3
93.3
86.6
N.A.
86.6
86.6
N.A.
20
66.6
60
13.3
N.A.
N.A.
26.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
40
86.6
93.3
20
N.A.
N.A.
53.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
9
0
0
9
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% D
% Glu:
0
0
0
92
0
9
0
0
0
0
59
0
67
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% H
% Ile:
75
0
0
0
9
0
50
0
0
0
0
0
0
9
0
% I
% Lys:
0
9
0
0
9
67
0
0
17
0
0
67
0
0
9
% K
% Leu:
0
75
0
0
9
9
9
17
0
9
0
0
0
59
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
0
67
0
0
0
0
50
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
9
0
9
17
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
9
0
0
0
0
0
59
0
0
9
0
0
0
% R
% Ser:
9
0
0
0
0
9
0
9
0
50
0
0
9
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
17
17
0
0
0
0
0
% T
% Val:
0
0
0
0
67
0
17
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
59
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _