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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP13A4
All Species:
36.36
Human Site:
Y222
Identified Species:
72.73
UniProt:
Q4VNC1
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4VNC1
NP_115655.2
1196
133973
Y222
C
L
W
F
S
E
D
Y
K
E
Y
A
F
A
I
Chimpanzee
Pan troglodytes
XP_516955
1196
134039
Y222
C
L
W
F
S
E
D
Y
K
E
Y
A
F
A
I
Rhesus Macaque
Macaca mulatta
XP_001086808
1184
131890
Y222
C
L
W
F
S
E
D
Y
K
E
Y
A
F
A
I
Dog
Lupus familis
XP_850465
1197
133945
Y223
C
L
W
F
S
E
D
Y
K
E
Y
A
F
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q5XF90
1193
132785
Y223
C
L
W
F
S
E
D
Y
K
E
Y
A
L
A
I
Rat
Rattus norvegicus
XP_001053714
1204
133858
Y234
C
L
W
F
S
E
D
Y
K
E
Y
A
L
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512080
1148
128692
Y221
C
L
W
F
G
E
D
Y
K
E
Y
A
A
A
I
Chicken
Gallus gallus
Q5ZKB7
1204
134040
Y220
C
L
W
F
A
E
D
Y
M
E
Y
A
A
A
I
Frog
Xenopus laevis
NP_001086889
1143
127992
Y219
C
L
W
F
A
E
E
Y
I
E
Y
S
V
A
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27533
1256
140883
F197
P
F
Y
V
F
Q
I
F
S
V
T
V
W
Y
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LT02
1179
131097
F218
G
L
W
C
L
D
E
F
W
Y
Y
S
V
F
T
Baker's Yeast
Sacchar. cerevisiae
Q12697
1472
166731
Y514
I
L
W
G
I
D
E
Y
Y
Y
Y
A
A
C
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
93.1
90.9
N.A.
87.1
84.9
N.A.
71.9
64.6
60.9
N.A.
N.A.
N.A.
N.A.
33.5
N.A.
Protein Similarity:
100
99.7
95.3
95.1
N.A.
92.4
91
N.A.
82.6
78.3
73.3
N.A.
N.A.
N.A.
N.A.
52.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
80
66.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
86.6
86.6
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
28.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.9
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
0
0
0
0
0
0
75
25
75
0
% A
% Cys:
75
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
0
17
67
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
75
25
0
0
75
0
0
0
0
0
% E
% Phe:
0
9
0
75
9
0
0
17
0
0
0
0
34
9
0
% F
% Gly:
9
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
9
0
9
0
9
0
0
0
0
0
84
% I
% Lys:
0
0
0
0
0
0
0
0
59
0
0
0
0
0
0
% K
% Leu:
0
92
0
0
9
0
0
0
0
0
0
0
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
50
0
0
0
9
0
0
17
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% T
% Val:
0
0
0
9
0
0
0
0
0
9
0
9
17
0
0
% V
% Trp:
0
0
92
0
0
0
0
0
9
0
0
0
9
0
0
% W
% Tyr:
0
0
9
0
0
0
0
84
9
17
92
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _