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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP13A4 All Species: 22.42
Human Site: T289 Identified Species: 44.85
UniProt: Q4VNC1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4VNC1 NP_115655.2 1196 133973 T289 P G D L L I L T G N K V L M P
Chimpanzee Pan troglodytes XP_516955 1196 134039 T289 P G D L L I L T G N K V L M P
Rhesus Macaque Macaca mulatta XP_001086808 1184 131890 T289 P G D L L I L T G N K V L M P
Dog Lupus familis XP_850465 1197 133945 T290 P G D L L V L T G N K V Q M P
Cat Felis silvestris
Mouse Mus musculus Q5XF90 1193 132785 T290 P G D L L I L T G S R V Q M P
Rat Rattus norvegicus XP_001053714 1204 133858 T301 P G D L L I L T G S R V Q M P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512080 1148 128692 L288 V P G D L L V L L G N K M Q L
Chicken Gallus gallus Q5ZKB7 1204 134040 E287 G D M V V L K E G K A L L P C
Frog Xenopus laevis NP_001086889 1143 127992 Q286 P G D I L V I Q R N T L L P C
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27533 1256 140883 P264 I G S D Q L V P G D I L L I P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LT02 1179 131097 S285 V V S I G R P S T Q T G G E D
Baker's Yeast Sacchar. cerevisiae Q12697 1472 166731 N581 I Y E V S D P N I T I L P C D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 93.1 90.9 N.A. 87.1 84.9 N.A. 71.9 64.6 60.9 N.A. N.A. N.A. N.A. 33.5 N.A.
Protein Similarity: 100 99.7 95.3 95.1 N.A. 92.4 91 N.A. 82.6 78.3 73.3 N.A. N.A. N.A. N.A. 52.8 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 80 80 N.A. 6.6 13.3 40 N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 26.6 40 66.6 N.A. N.A. N.A. N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.8 28.8 N.A.
Protein Similarity: N.A. N.A. N.A. 43.9 46.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 17 % C
% Asp: 0 9 59 17 0 9 0 0 0 9 0 0 0 0 17 % D
% Glu: 0 0 9 0 0 0 0 9 0 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 67 9 0 9 0 0 0 67 9 0 9 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 17 0 0 17 0 42 9 0 9 0 17 0 0 9 0 % I
% Lys: 0 0 0 0 0 0 9 0 0 9 34 9 0 0 0 % K
% Leu: 0 0 0 50 67 25 50 9 9 0 0 34 50 0 9 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 9 50 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 42 9 0 0 0 0 % N
% Pro: 59 9 0 0 0 0 17 9 0 0 0 0 9 17 59 % P
% Gln: 0 0 0 0 9 0 0 9 0 9 0 0 25 9 0 % Q
% Arg: 0 0 0 0 0 9 0 0 9 0 17 0 0 0 0 % R
% Ser: 0 0 17 0 9 0 0 9 0 17 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 50 9 9 17 0 0 0 0 % T
% Val: 17 9 0 17 9 17 17 0 0 0 0 50 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _