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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP13A4
All Species:
15.15
Human Site:
S586
Identified Species:
30.3
UniProt:
Q4VNC1
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4VNC1
NP_115655.2
1196
133973
S586
V
K
P
C
R
T
A
S
Q
V
P
V
E
G
I
Chimpanzee
Pan troglodytes
XP_516955
1196
134039
S586
V
K
P
C
R
T
A
S
Q
V
P
V
E
G
I
Rhesus Macaque
Macaca mulatta
XP_001086808
1184
131890
S586
V
K
P
C
R
T
A
S
Q
V
P
V
E
G
I
Dog
Lupus familis
XP_850465
1197
133945
S587
V
K
P
C
E
T
A
S
Q
V
P
V
E
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q5XF90
1193
132785
G587
V
K
P
T
D
M
V
G
Q
V
P
A
E
G
L
Rat
Rattus norvegicus
XP_001053714
1204
133858
G598
V
K
P
P
D
T
V
G
Q
V
P
A
E
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512080
1148
128692
K580
T
S
Q
A
L
I
V
K
P
G
H
T
D
T
Q
Chicken
Gallus gallus
Q5ZKB7
1204
134040
N583
I
R
P
G
P
K
A
N
T
A
S
V
D
G
I
Frog
Xenopus laevis
NP_001086889
1143
127992
H577
Q
R
I
V
K
P
G
H
N
T
S
S
D
A
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27533
1256
140883
I579
F
D
N
V
Q
P
S
I
I
K
P
T
D
D
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LT02
1179
131097
S586
M
Q
R
Y
H
F
A
S
H
L
K
R
M
S
V
Baker's Yeast
Sacchar. cerevisiae
Q12697
1472
166731
Q878
W
S
F
E
E
D
F
Q
K
R
A
F
H
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
93.1
90.9
N.A.
87.1
84.9
N.A.
71.9
64.6
60.9
N.A.
N.A.
N.A.
N.A.
33.5
N.A.
Protein Similarity:
100
99.7
95.3
95.1
N.A.
92.4
91
N.A.
82.6
78.3
73.3
N.A.
N.A.
N.A.
N.A.
52.8
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
53.3
60
N.A.
0
33.3
6.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
60
66.6
N.A.
6.6
60
26.6
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
28.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.9
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
50
0
0
9
9
17
0
9
0
% A
% Cys:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
17
9
0
0
0
0
0
0
34
9
0
% D
% Glu:
0
0
0
9
17
0
0
0
0
0
0
0
50
0
0
% E
% Phe:
9
0
9
0
0
9
9
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
9
0
0
9
17
0
9
0
0
0
59
0
% G
% His:
0
0
0
0
9
0
0
9
9
0
9
0
9
0
0
% H
% Ile:
9
0
9
0
0
9
0
9
9
0
0
0
0
0
50
% I
% Lys:
0
50
0
0
9
9
0
9
9
9
9
0
0
0
9
% K
% Leu:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
25
% L
% Met:
9
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
9
0
0
0
0
9
9
0
0
0
0
0
0
% N
% Pro:
0
0
59
9
9
17
0
0
9
0
59
0
0
0
0
% P
% Gln:
9
9
9
0
9
0
0
9
50
0
0
0
0
0
9
% Q
% Arg:
0
17
9
0
25
0
0
0
0
9
0
9
0
0
0
% R
% Ser:
0
17
0
0
0
0
9
42
0
0
17
9
0
17
0
% S
% Thr:
9
0
0
9
0
42
0
0
9
9
0
17
0
9
0
% T
% Val:
50
0
0
17
0
0
25
0
0
50
0
42
0
0
9
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _