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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP13A4 All Species: 9.09
Human Site: S1173 Identified Species: 18.18
UniProt: Q4VNC1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4VNC1 NP_115655.2 1196 133973 S1173 P L N Q T S H S D M P E C G R
Chimpanzee Pan troglodytes XP_516955 1196 134039 S1173 P L N Q T S H S D M P E C G R
Rhesus Macaque Macaca mulatta XP_001086808 1184 131890 A1159 S R E Q D E P A Q F T L Q C A
Dog Lupus familis XP_850465 1197 133945 S1174 L L N Q M S Y S D T P G C E S
Cat Felis silvestris
Mouse Mus musculus Q5XF90 1193 132785 Q1170 S S W P P L N Q T S Y S D M Q
Rat Rattus norvegicus XP_001053714 1204 133858 Q1181 S S W P P L N Q T S Y S D M Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512080 1148 128692 V1124 M L A V N F A V S L I F E G H
Chicken Gallus gallus Q5ZKB7 1204 134040 L1178 P L N E T F S L D A V T V S V
Frog Xenopus laevis NP_001086889 1143 127992 S1121 E L L E S C C S S H W Q C L T
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27533 1256 140883 G1229 R L I S R I G G E P T W L T N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LT02 1179 131097 A1154 W E R L L R W A F P G K I S S
Baker's Yeast Sacchar. cerevisiae Q12697 1472 166731 G1448 Y I P P S I K G W L K K K K S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 93.1 90.9 N.A. 87.1 84.9 N.A. 71.9 64.6 60.9 N.A. N.A. N.A. N.A. 33.5 N.A.
Protein Similarity: 100 99.7 95.3 95.1 N.A. 92.4 91 N.A. 82.6 78.3 73.3 N.A. N.A. N.A. N.A. 52.8 N.A.
P-Site Identity: 100 100 6.6 53.3 N.A. 0 0 N.A. 13.3 33.3 20 N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 13.3 60 N.A. 13.3 13.3 N.A. 20 40 40 N.A. N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.8 28.8 N.A.
Protein Similarity: N.A. N.A. N.A. 43.9 46.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 9 17 0 9 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 9 9 0 0 0 0 0 34 9 0 % C
% Asp: 0 0 0 0 9 0 0 0 34 0 0 0 17 0 0 % D
% Glu: 9 9 9 17 0 9 0 0 9 0 0 17 9 9 0 % E
% Phe: 0 0 0 0 0 17 0 0 9 9 0 9 0 0 0 % F
% Gly: 0 0 0 0 0 0 9 17 0 0 9 9 0 25 0 % G
% His: 0 0 0 0 0 0 17 0 0 9 0 0 0 0 9 % H
% Ile: 0 9 9 0 0 17 0 0 0 0 9 0 9 0 0 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 9 17 9 9 0 % K
% Leu: 9 59 9 9 9 17 0 9 0 17 0 9 9 9 0 % L
% Met: 9 0 0 0 9 0 0 0 0 17 0 0 0 17 0 % M
% Asn: 0 0 34 0 9 0 17 0 0 0 0 0 0 0 9 % N
% Pro: 25 0 9 25 17 0 9 0 0 17 25 0 0 0 0 % P
% Gln: 0 0 0 34 0 0 0 17 9 0 0 9 9 0 17 % Q
% Arg: 9 9 9 0 9 9 0 0 0 0 0 0 0 0 17 % R
% Ser: 25 17 0 9 17 25 9 34 17 17 0 17 0 17 25 % S
% Thr: 0 0 0 0 25 0 0 0 17 9 17 9 0 9 9 % T
% Val: 0 0 0 9 0 0 0 9 0 0 9 0 9 0 9 % V
% Trp: 9 0 17 0 0 0 9 0 9 0 9 9 0 0 0 % W
% Tyr: 9 0 0 0 0 0 9 0 0 0 17 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _