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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCTD21 All Species: 28.48
Human Site: T126 Identified Species: 69.63
UniProt: Q4G0X4 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4G0X4 NP_001025030.1 260 29643 T126 R V Q T V H F T V R E A P Q I
Chimpanzee Pan troglodytes XP_523831 232 25841 S104 S P R L V H F S A R R G P H H
Rhesus Macaque Macaca mulatta XP_001093230 260 29621 T126 H V Q T V H F T V R E A P Q I
Dog Lupus familis XP_851103 260 29610 T126 R V Q T V H F T V R E A P Q I
Cat Felis silvestris
Mouse Mus musculus NP_001034128 260 29639 T126 R V Q T V H F T V R E A P Q I
Rat Rattus norvegicus NP_001102621 260 29605 T126 H V Q T V H F T V R E A P Q I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519321 396 44413 T126 R V Q T V H F T V R E A P Q I
Chicken Gallus gallus XP_425657 260 29738 T126 K T Q T V H F T V R E A P Q I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001074463 237 27671 P110 Q C L G E T K P L Y P L D T F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190874 218 25162 E91 A D F Y Q I K E L I D A V A Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.7 99.2 99.6 N.A. 99.6 98.4 N.A. 58.3 91.1 N.A. 37.3 N.A. N.A. N.A. N.A. 34.6
Protein Similarity: 100 51.1 99.6 100 N.A. 99.6 98.8 N.A. 63.8 98 N.A. 53.4 N.A. N.A. N.A. N.A. 50.7
P-Site Identity: 100 33.3 93.3 100 N.A. 100 93.3 N.A. 100 86.6 N.A. 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 46.6 93.3 100 N.A. 100 93.3 N.A. 100 93.3 N.A. 13.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 10 0 0 80 0 10 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 10 0 10 0 0 % D
% Glu: 0 0 0 0 10 0 0 10 0 0 70 0 0 0 0 % E
% Phe: 0 0 10 0 0 0 80 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 20 0 0 0 0 80 0 0 0 0 0 0 0 10 10 % H
% Ile: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 70 % I
% Lys: 10 0 0 0 0 0 20 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 10 0 0 0 0 20 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 0 0 0 10 0 0 10 0 80 0 0 % P
% Gln: 10 0 70 0 10 0 0 0 0 0 0 0 0 70 10 % Q
% Arg: 40 0 10 0 0 0 0 0 0 80 10 0 0 0 0 % R
% Ser: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % S
% Thr: 0 10 0 70 0 10 0 70 0 0 0 0 0 10 0 % T
% Val: 0 60 0 0 80 0 0 0 70 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _