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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD21
All Species:
27.27
Human Site:
S139
Identified Species:
66.67
UniProt:
Q4G0X4
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4G0X4
NP_001025030.1
260
29643
S139
Q
I
Y
S
L
S
S
S
S
M
E
V
F
N
A
Chimpanzee
Pan troglodytes
XP_523831
232
25841
V117
H
H
Y
E
L
S
S
V
Q
V
D
T
F
R
A
Rhesus Macaque
Macaca mulatta
XP_001093230
260
29621
S139
Q
I
Y
S
L
S
S
S
S
M
E
V
F
N
A
Dog
Lupus familis
XP_851103
260
29610
S139
Q
I
Y
S
L
S
S
S
S
M
E
V
F
N
A
Cat
Felis silvestris
Mouse
Mus musculus
NP_001034128
260
29639
S139
Q
I
Y
S
L
S
S
S
S
M
E
V
F
N
A
Rat
Rattus norvegicus
NP_001102621
260
29605
S139
Q
I
Y
S
L
S
S
S
S
M
E
V
F
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519321
396
44413
S139
Q
I
Y
S
L
S
S
S
N
M
E
V
F
S
A
Chicken
Gallus gallus
XP_425657
260
29738
S139
Q
I
Y
S
L
S
S
S
N
M
E
V
F
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074463
237
27671
L123
T
F
E
Q
V
V
E
L
S
S
T
R
K
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190874
218
25162
K104
A
Q
I
R
N
R
E
K
E
K
R
A
K
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.7
99.2
99.6
N.A.
99.6
98.4
N.A.
58.3
91.1
N.A.
37.3
N.A.
N.A.
N.A.
N.A.
34.6
Protein Similarity:
100
51.1
99.6
100
N.A.
99.6
98.8
N.A.
63.8
98
N.A.
53.4
N.A.
N.A.
N.A.
N.A.
50.7
P-Site Identity:
100
40
100
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
53.3
100
100
N.A.
100
100
N.A.
100
100
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
80
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
10
10
0
0
20
0
10
0
70
0
0
0
10
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
80
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
70
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
10
0
0
20
0
0
% K
% Leu:
0
0
0
0
80
0
0
10
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
70
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
20
0
0
0
0
50
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
70
10
0
10
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
10
0
0
0
0
10
10
0
10
0
% R
% Ser:
0
0
0
70
0
80
80
70
60
10
0
0
0
30
10
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% T
% Val:
0
0
0
0
10
10
0
10
0
10
0
70
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _