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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SUV420H1
All Species:
28.18
Human Site:
Y821
Identified Species:
56.36
UniProt:
Q4FZB7
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4FZB7
NP_057112.3
885
99187
Y821
E
V
D
D
Y
S
Q
Y
E
E
E
S
T
D
D
Chimpanzee
Pan troglodytes
XP_001173516
885
99214
Y821
E
V
D
D
Y
S
Q
Y
E
E
E
S
T
D
D
Rhesus Macaque
Macaca mulatta
XP_001103268
885
99191
Y821
E
V
D
D
Y
S
Q
Y
E
E
E
S
T
D
D
Dog
Lupus familis
XP_851524
885
98359
Y821
E
V
D
D
Y
S
Q
Y
E
E
E
S
T
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3U8K7
883
98562
Y819
E
V
D
D
Y
S
Q
Y
E
E
D
S
T
D
E
Rat
Rattus norvegicus
P0C2N5
883
98649
Y819
E
V
D
D
Y
S
Q
Y
E
E
D
S
T
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422910
1115
126312
Y1052
E
V
D
D
Y
A
Q
Y
E
E
E
T
A
D
E
Frog
Xenopus laevis
Q6GP17
855
97576
E793
D
G
Y
D
H
Y
E
E
E
S
V
E
E
S
S
Zebra Danio
Brachydanio rerio
Q5U3H2
808
90420
S755
G
Q
D
M
E
V
E
S
M
S
S
E
D
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W5E0
1300
137506
E1013
E
H
G
N
D
D
D
E
D
E
E
E
D
D
E
Honey Bee
Apis mellifera
XP_395375
977
111827
T890
R
T
G
R
L
K
L
T
L
R
M
K
R
S
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800216
932
103465
A832
F
Q
P
K
N
A
P
A
P
F
Q
L
P
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
90.7
N.A.
87.2
87.3
N.A.
N.A.
57.8
70.9
55.1
N.A.
25.1
28.3
N.A.
32
Protein Similarity:
100
99.6
99.6
94
N.A.
93.2
92.7
N.A.
N.A.
66.5
80.5
66.7
N.A.
38
46.6
N.A.
49
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
73.3
13.3
20
N.A.
26.6
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
33.3
26.6
N.A.
46.6
0
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
0
9
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
67
67
9
9
9
0
9
0
17
0
17
75
42
% D
% Glu:
67
0
0
0
9
0
17
17
67
67
50
25
9
0
34
% E
% Phe:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
9
9
17
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
9
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
0
0
0
9
0
9
0
9
0
0
9
0
0
9
% L
% Met:
0
0
0
9
0
0
0
0
9
0
9
0
0
0
0
% M
% Asn:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
9
0
9
0
0
0
9
0
9
% P
% Gln:
0
17
0
0
0
0
59
0
0
0
9
0
0
0
0
% Q
% Arg:
9
0
0
9
0
0
0
0
0
9
0
0
9
0
0
% R
% Ser:
0
0
0
0
0
50
0
9
0
17
9
50
0
25
9
% S
% Thr:
0
9
0
0
0
0
0
9
0
0
0
9
50
0
0
% T
% Val:
0
59
0
0
0
9
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
59
9
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _