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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SUV420H1
All Species:
10.91
Human Site:
T630
Identified Species:
21.82
UniProt:
Q4FZB7
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4FZB7
NP_057112.3
885
99187
T630
F
A
K
I
E
E
S
T
P
V
H
D
S
P
G
Chimpanzee
Pan troglodytes
XP_001173516
885
99214
T630
F
A
K
I
E
E
S
T
P
V
H
D
F
P
G
Rhesus Macaque
Macaca mulatta
XP_001103268
885
99191
T630
F
A
K
I
E
E
S
T
P
V
R
D
S
P
G
Dog
Lupus familis
XP_851524
885
98359
G630
K
A
E
E
A
A
V
G
Q
E
S
P
G
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3U8K7
883
98562
D628
K
H
L
A
K
T
E
D
C
S
P
E
H
S
F
Rat
Rattus norvegicus
P0C2N5
883
98649
C628
H
L
A
K
T
E
D
C
S
P
E
H
S
F
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422910
1115
126312
T861
P
P
A
K
L
D
E
T
D
N
T
H
N
T
P
Frog
Xenopus laevis
Q6GP17
855
97576
S602
S
K
V
E
D
S
V
S
S
V
Y
D
Q
S
S
Zebra Danio
Brachydanio rerio
Q5U3H2
808
90420
E564
R
R
R
T
V
K
Q
E
D
S
Y
G
E
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W5E0
1300
137506
N822
P
S
S
T
S
S
E
N
Q
Q
Q
Q
A
T
R
Honey Bee
Apis mellifera
XP_395375
977
111827
E699
K
S
A
I
S
E
T
E
E
L
E
S
V
T
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800216
932
103465
A641
D
Y
L
D
A
V
D
A
V
Y
S
T
P
N
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
90.7
N.A.
87.2
87.3
N.A.
N.A.
57.8
70.9
55.1
N.A.
25.1
28.3
N.A.
32
Protein Similarity:
100
99.6
99.6
94
N.A.
93.2
92.7
N.A.
N.A.
66.5
80.5
66.7
N.A.
38
46.6
N.A.
49
P-Site Identity:
100
93.3
93.3
6.6
N.A.
0
13.3
N.A.
N.A.
6.6
13.3
0
N.A.
0
13.3
N.A.
0
P-Site Similarity:
100
93.3
93.3
13.3
N.A.
13.3
13.3
N.A.
N.A.
20
33.3
20
N.A.
13.3
33.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
25
9
17
9
0
9
0
0
0
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
9
9
17
9
17
0
0
34
0
0
0
% D
% Glu:
0
0
9
17
25
42
25
17
9
9
17
9
9
9
9
% E
% Phe:
25
0
0
0
0
0
0
0
0
0
0
0
9
9
17
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
9
9
0
25
% G
% His:
9
9
0
0
0
0
0
0
0
0
17
17
9
0
9
% H
% Ile:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
25
9
25
17
9
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
17
0
9
0
0
0
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
9
0
0
9
9
0
% N
% Pro:
17
9
0
0
0
0
0
0
25
9
9
9
9
25
17
% P
% Gln:
0
0
0
0
0
0
9
0
17
9
9
9
9
0
0
% Q
% Arg:
9
9
9
0
0
0
0
0
0
0
9
0
0
0
9
% R
% Ser:
9
17
9
0
17
17
25
9
17
17
17
9
25
25
9
% S
% Thr:
0
0
0
17
9
9
9
34
0
0
9
9
0
25
0
% T
% Val:
0
0
9
0
9
9
17
0
9
34
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
9
17
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _