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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SUV420H1
All Species:
26.67
Human Site:
T425
Identified Species:
53.33
UniProt:
Q4FZB7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4FZB7
NP_057112.3
885
99187
T425
I
P
A
S
S
N
S
T
S
S
K
L
T
H
I
Chimpanzee
Pan troglodytes
XP_001173516
885
99214
T425
I
P
A
S
S
N
S
T
S
S
K
L
T
H
I
Rhesus Macaque
Macaca mulatta
XP_001103268
885
99191
T425
I
P
A
S
S
N
S
T
S
S
K
L
T
H
I
Dog
Lupus familis
XP_851524
885
98359
T425
I
P
A
S
S
N
S
T
S
S
K
L
T
H
I
Cat
Felis silvestris
Mouse
Mus musculus
Q3U8K7
883
98562
T426
V
P
A
A
S
N
S
T
S
P
K
L
V
H
T
Rat
Rattus norvegicus
P0C2N5
883
98649
T425
V
P
A
A
S
N
S
T
S
P
K
L
V
H
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422910
1115
126312
S660
P
A
S
S
N
S
T
S
S
K
L
T
H
I
N
Frog
Xenopus laevis
Q6GP17
855
97576
K401
S
S
S
S
T
S
S
K
L
P
H
I
N
N
S
Zebra Danio
Brachydanio rerio
Q5U3H2
808
90420
S376
L
R
K
R
T
S
Q
S
C
V
K
K
H
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W5E0
1300
137506
Q483
M
L
P
T
P
S
Q
Q
S
T
G
G
K
E
A
Honey Bee
Apis mellifera
XP_395375
977
111827
S484
I
L
E
Q
S
T
C
S
N
L
Q
R
E
Y
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800216
932
103465
Q426
V
I
G
P
A
S
R
Q
R
R
D
R
Q
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
90.7
N.A.
87.2
87.3
N.A.
N.A.
57.8
70.9
55.1
N.A.
25.1
28.3
N.A.
32
Protein Similarity:
100
99.6
99.6
94
N.A.
93.2
92.7
N.A.
N.A.
66.5
80.5
66.7
N.A.
38
46.6
N.A.
49
P-Site Identity:
100
100
100
100
N.A.
66.6
66.6
N.A.
N.A.
13.3
13.3
6.6
N.A.
6.6
13.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
80
86.6
N.A.
N.A.
46.6
46.6
33.3
N.A.
33.3
40
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
50
17
9
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
0
0
9
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
9
9
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
17
50
0
% H
% Ile:
42
9
0
0
0
0
0
0
0
0
0
9
0
9
34
% I
% Lys:
0
0
9
0
0
0
0
9
0
9
59
9
9
0
0
% K
% Leu:
9
17
0
0
0
0
0
0
9
9
9
50
0
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
9
50
0
0
9
0
0
0
9
9
17
% N
% Pro:
9
50
9
9
9
0
0
0
0
25
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
17
17
0
0
9
0
9
0
0
% Q
% Arg:
0
9
0
9
0
0
9
0
9
9
0
17
0
0
0
% R
% Ser:
9
9
17
50
59
42
59
25
67
34
0
0
0
9
9
% S
% Thr:
0
0
0
9
17
9
9
50
0
9
0
9
34
0
9
% T
% Val:
25
0
0
0
0
0
0
0
0
9
0
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _