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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUV420H1 All Species: 29.39
Human Site: S741 Identified Species: 58.79
UniProt: Q4FZB7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4FZB7 NP_057112.3 885 99187 S741 E N D G M N S S K I S I K L S
Chimpanzee Pan troglodytes XP_001173516 885 99214 S741 E N D G M N S S K I S I K L S
Rhesus Macaque Macaca mulatta XP_001103268 885 99191 S741 E N D G M N S S K I S I K L S
Dog Lupus familis XP_851524 885 98359 S741 E N D G M N S S K I S I K L S
Cat Felis silvestris
Mouse Mus musculus Q3U8K7 883 98562 S739 E S D G V N S S K I S I K L S
Rat Rattus norvegicus P0C2N5 883 98649 S739 E S D S V N S S K I S I K L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422910 1115 126312 S972 E S D G M N S S K I S I K L S
Frog Xenopus laevis Q6GP17 855 97576 S713 K E N E G M S S S K I S I K L
Zebra Danio Brachydanio rerio Q5U3H2 808 90420 S675 S K I S I K F S K E H E K D R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W5E0 1300 137506 R933 P L L K T P E R R L K L T L R
Honey Bee Apis mellifera XP_395375 977 111827 V810 C N K V E P P V L L P Q E P W
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_800216 932 103465 E752 K D P N G D I E E V V T S S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99 90.7 N.A. 87.2 87.3 N.A. N.A. 57.8 70.9 55.1 N.A. 25.1 28.3 N.A. 32
Protein Similarity: 100 99.6 99.6 94 N.A. 93.2 92.7 N.A. N.A. 66.5 80.5 66.7 N.A. 38 46.6 N.A. 49
P-Site Identity: 100 100 100 100 N.A. 86.6 80 N.A. N.A. 93.3 13.3 20 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 100 26.6 26.6 N.A. 26.6 20 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 59 0 0 9 0 0 0 0 0 0 0 9 0 % D
% Glu: 59 9 0 9 9 0 9 9 9 9 0 9 9 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 50 17 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 9 0 9 0 9 0 0 59 9 59 9 0 0 % I
% Lys: 17 9 9 9 0 9 0 0 67 9 9 0 67 9 0 % K
% Leu: 0 9 9 0 0 0 0 0 9 17 0 9 0 67 9 % L
% Met: 0 0 0 0 42 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 42 9 9 0 59 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 9 0 0 17 9 0 0 0 9 0 0 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 17 % R
% Ser: 9 25 0 17 0 0 67 75 9 0 59 9 9 9 67 % S
% Thr: 0 0 0 0 9 0 0 0 0 0 0 9 9 0 0 % T
% Val: 0 0 0 9 17 0 0 9 0 9 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _