KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SUV420H1
All Species:
23.94
Human Site:
S414
Identified Species:
47.88
UniProt:
Q4FZB7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4FZB7
NP_057112.3
885
99187
S414
S
R
T
L
T
R
Q
S
M
S
R
I
P
A
S
Chimpanzee
Pan troglodytes
XP_001173516
885
99214
S414
S
R
T
L
T
R
Q
S
M
S
R
I
P
A
S
Rhesus Macaque
Macaca mulatta
XP_001103268
885
99191
S414
S
R
T
L
T
R
Q
S
M
S
R
I
P
A
S
Dog
Lupus familis
XP_851524
885
98359
S414
S
R
T
L
T
R
Q
S
M
S
R
I
P
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3U8K7
883
98562
S415
S
R
A
L
T
R
P
S
M
P
R
V
P
A
A
Rat
Rattus norvegicus
P0C2N5
883
98649
S414
S
R
A
L
T
R
Q
S
M
P
R
V
P
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422910
1115
126312
I649
R
T
L
T
R
Q
S
I
S
R
I
P
A
S
S
Frog
Xenopus laevis
Q6GP17
855
97576
R390
L
R
R
R
S
M
S
R
I
P
V
S
S
S
S
Zebra Danio
Brachydanio rerio
Q5U3H2
808
90420
V365
D
S
Q
E
P
T
T
V
Q
T
S
L
R
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W5E0
1300
137506
T472
S
G
G
A
G
G
A
T
G
A
A
M
L
P
T
Honey Bee
Apis mellifera
XP_395375
977
111827
S473
N
I
C
H
V
Q
T
S
C
H
D
I
L
E
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800216
932
103465
K415
R
S
L
R
S
R
R
K
L
E
D
V
I
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
90.7
N.A.
87.2
87.3
N.A.
N.A.
57.8
70.9
55.1
N.A.
25.1
28.3
N.A.
32
Protein Similarity:
100
99.6
99.6
94
N.A.
93.2
92.7
N.A.
N.A.
66.5
80.5
66.7
N.A.
38
46.6
N.A.
49
P-Site Identity:
100
100
100
100
N.A.
66.6
73.3
N.A.
N.A.
6.6
13.3
0
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
80
86.6
N.A.
N.A.
20
33.3
13.3
N.A.
33.3
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
9
0
0
9
0
0
9
9
0
9
50
17
% A
% Cys:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
0
0
0
9
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
9
9
0
0
9
0
0
0
0
9
0
% G
% His:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
9
9
0
9
42
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% K
% Leu:
9
0
17
50
0
0
0
0
9
0
0
9
17
0
0
% L
% Met:
0
0
0
0
0
9
0
0
50
0
0
9
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
9
0
0
25
0
9
50
9
9
% P
% Gln:
0
0
9
0
0
17
42
0
9
0
0
0
0
0
9
% Q
% Arg:
17
59
9
17
9
59
9
9
0
9
50
0
9
0
9
% R
% Ser:
59
17
0
0
17
0
17
59
9
34
9
9
9
17
50
% S
% Thr:
0
9
34
9
50
9
17
9
0
9
0
0
0
0
9
% T
% Val:
0
0
0
0
9
0
0
9
0
0
9
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _