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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUV420H1 All Species: 25.15
Human Site: S405 Identified Species: 50.3
UniProt: Q4FZB7 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4FZB7 NP_057112.3 885 99187 S405 S V G V K K N S K S R T L T R
Chimpanzee Pan troglodytes XP_001173516 885 99214 S405 S V G V K K N S K S R T L T R
Rhesus Macaque Macaca mulatta XP_001103268 885 99191 S405 S V G V K K N S K S R T L T R
Dog Lupus familis XP_851524 885 98359 S405 S V G V K K N S K S R T L T R
Cat Felis silvestris
Mouse Mus musculus Q3U8K7 883 98562 S406 S V G V K K S S K S R A L T R
Rat Rattus norvegicus P0C2N5 883 98649 S405 S V G V K K N S K S R A L T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422910 1115 126312 K382 I G V K K N G K N R T L T R Q
Frog Xenopus laevis Q6GP17 855 97576 R381 M R K R S K S R T L R R R S M
Zebra Danio Brachydanio rerio Q5U3H2 808 90420 E356 Q S V S S N A E A D S Q E P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W5E0 1300 137506 V463 T S S T N G L V A S G G A G G
Honey Bee Apis mellifera XP_395375 977 111827 T464 R N T L N E E T N N I C H V Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_800216 932 103465 S406 R V L V A G G S G R S L R S R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99 90.7 N.A. 87.2 87.3 N.A. N.A. 57.8 70.9 55.1 N.A. 25.1 28.3 N.A. 32
Protein Similarity: 100 99.6 99.6 94 N.A. 93.2 92.7 N.A. N.A. 66.5 80.5 66.7 N.A. 38 46.6 N.A. 49
P-Site Identity: 100 100 100 100 N.A. 86.6 93.3 N.A. N.A. 6.6 13.3 0 N.A. 6.6 0 N.A. 26.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 13.3 26.6 0 N.A. 13.3 33.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 9 0 17 0 0 17 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 9 9 9 0 0 0 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 50 0 0 17 17 0 9 0 9 9 0 9 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % I
% Lys: 0 0 9 9 59 59 0 9 50 0 0 0 0 0 0 % K
% Leu: 0 0 9 9 0 0 9 0 0 9 0 17 50 0 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 9 0 0 17 17 42 0 17 9 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % P
% Gln: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 17 % Q
% Arg: 17 9 0 9 0 0 0 9 0 17 59 9 17 9 59 % R
% Ser: 50 17 9 9 17 0 17 59 0 59 17 0 0 17 0 % S
% Thr: 9 0 9 9 0 0 0 9 9 0 9 34 9 50 9 % T
% Val: 0 59 17 59 0 0 0 9 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _