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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTDC1
All Species:
9.09
Human Site:
S412
Identified Species:
25
UniProt:
Q4AE62
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4AE62
NP_001006637.1
458
52597
S412
Y
S
T
P
E
Q
L
S
K
R
L
Q
N
F
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541028
455
52013
S409
Y
S
T
P
E
Q
L
S
K
R
L
Q
N
F
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW56
445
50998
S399
Y
S
T
P
E
Q
L
S
K
R
L
K
S
F
C
Rat
Rattus norvegicus
Q53E76
389
44639
K347
E
Q
L
S
K
R
L
K
S
F
C
E
R
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI40
382
43803
I340
V
P
G
W
K
R
C
I
V
A
V
T
R
C
V
Frog
Xenopus laevis
Q4V7R4
437
50486
L391
Y
S
S
P
E
Q
L
L
R
K
L
E
D
F
C
Zebra Danio
Brachydanio rerio
Q568B7
433
49719
P391
L
Q
E
F
C
K
R
P
Q
L
A
R
Q
H
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXN0
377
44139
M335
K
L
Y
N
F
C
R
M
P
R
V
F
R
K
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782342
270
30415
C228
P
D
C
T
L
A
A
C
Q
H
H
Y
C
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
88.2
N.A.
78.5
69.4
N.A.
N.A.
54.1
63.7
59.8
N.A.
43
N.A.
N.A.
32.5
Protein Similarity:
100
N.A.
N.A.
92.1
N.A.
85.8
75.9
N.A.
N.A.
66.1
77.5
74.4
N.A.
57.2
N.A.
N.A.
41
P-Site Identity:
100
N.A.
N.A.
100
N.A.
86.6
6.6
N.A.
N.A.
0
60
0
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
26.6
N.A.
N.A.
20
93.3
20
N.A.
13.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
12
0
0
12
12
0
0
0
0
% A
% Cys:
0
0
12
0
12
12
12
12
0
0
12
0
12
12
45
% C
% Asp:
0
12
0
0
0
0
0
0
0
0
0
0
12
0
12
% D
% Glu:
12
0
12
0
45
0
0
0
0
0
0
23
0
0
0
% E
% Phe:
0
0
0
12
12
0
0
0
0
12
0
12
0
45
0
% F
% Gly:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
12
12
0
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
0
23
12
0
12
34
12
0
12
0
12
0
% K
% Leu:
12
12
12
0
12
0
56
12
0
12
45
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
0
0
0
0
23
0
0
% N
% Pro:
12
12
0
45
0
0
0
12
12
0
0
0
0
12
0
% P
% Gln:
0
23
0
0
0
45
0
0
23
0
0
23
12
12
12
% Q
% Arg:
0
0
0
0
0
23
23
0
12
45
0
12
34
0
0
% R
% Ser:
0
45
12
12
0
0
0
34
12
0
0
0
12
0
0
% S
% Thr:
0
0
34
12
0
0
0
0
0
0
0
12
0
0
0
% T
% Val:
12
0
0
0
0
0
0
0
12
0
23
0
0
0
23
% V
% Trp:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
45
0
12
0
0
0
0
0
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _