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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTDC1
All Species:
3.03
Human Site:
S249
Identified Species:
8.33
UniProt:
Q4AE62
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4AE62
NP_001006637.1
458
52597
S249
Q
E
S
D
L
K
K
S
T
S
S
D
N
S
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541028
455
52013
S249
A
L
R
T
C
N
S
S
D
N
S
S
S
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW56
445
50998
S249
K
S
G
S
L
P
V
S
K
E
N
L
P
L
D
Rat
Rattus norvegicus
Q53E76
389
44639
L205
A
L
G
H
S
T
F
L
C
G
A
E
D
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI40
382
43803
Y198
V
K
R
N
G
D
F
Y
Q
R
E
G
L
P
G
Frog
Xenopus laevis
Q4V7R4
437
50486
H248
G
V
D
H
V
I
L
H
S
Q
S
T
L
A
G
Zebra Danio
Brachydanio rerio
Q568B7
433
49719
E248
P
L
C
G
H
E
G
E
K
L
R
P
L
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXN0
377
44139
D193
V
K
G
E
T
A
E
D
L
D
E
K
C
I
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782342
270
30415
L86
N
F
A
E
L
V
A
L
R
P
D
L
A
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
88.2
N.A.
78.5
69.4
N.A.
N.A.
54.1
63.7
59.8
N.A.
43
N.A.
N.A.
32.5
Protein Similarity:
100
N.A.
N.A.
92.1
N.A.
85.8
75.9
N.A.
N.A.
66.1
77.5
74.4
N.A.
57.2
N.A.
N.A.
41
P-Site Identity:
100
N.A.
N.A.
13.3
N.A.
13.3
0
N.A.
N.A.
0
6.6
0
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
26.6
N.A.
26.6
20
N.A.
N.A.
13.3
26.6
6.6
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
12
0
0
12
12
0
0
0
12
0
12
12
0
% A
% Cys:
0
0
12
0
12
0
0
0
12
0
0
0
12
0
0
% C
% Asp:
0
0
12
12
0
12
0
12
12
12
12
12
12
0
12
% D
% Glu:
0
12
0
23
0
12
12
12
0
12
23
12
0
0
0
% E
% Phe:
0
12
0
0
0
0
23
0
0
0
0
0
0
0
12
% F
% Gly:
12
0
34
12
12
0
12
0
0
12
0
12
0
12
23
% G
% His:
0
0
0
23
12
0
0
12
0
0
0
0
0
23
12
% H
% Ile:
0
0
0
0
0
12
0
0
0
0
0
0
0
12
12
% I
% Lys:
12
23
0
0
0
12
12
0
23
0
0
12
0
0
0
% K
% Leu:
0
34
0
0
34
0
12
23
12
12
0
23
34
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
12
0
12
0
0
0
12
12
0
12
0
0
% N
% Pro:
12
0
0
0
0
12
0
0
0
12
0
12
12
12
0
% P
% Gln:
12
0
0
0
0
0
0
0
12
12
0
0
0
12
12
% Q
% Arg:
0
0
23
0
0
0
0
0
12
12
12
0
0
0
0
% R
% Ser:
0
12
12
12
12
0
12
34
12
12
34
12
12
12
12
% S
% Thr:
0
0
0
12
12
12
0
0
12
0
0
12
0
0
0
% T
% Val:
23
12
0
0
12
12
12
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _