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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRY2
All Species:
35.45
Human Site:
T441
Identified Species:
60
UniProt:
Q49AN0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q49AN0
NP_001120929.1
593
66947
T441
P
V
G
F
G
R
R
T
D
P
S
G
D
Y
I
Chimpanzee
Pan troglodytes
XP_001160595
593
66872
T441
P
V
G
F
G
R
R
T
D
P
S
G
D
Y
I
Rhesus Macaque
Macaca mulatta
XP_001113162
593
66839
T441
P
V
G
F
G
R
R
T
D
P
S
G
D
Y
I
Dog
Lupus familis
XP_540761
593
66822
T441
P
V
G
F
G
R
R
T
D
P
S
G
D
Y
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9R194
592
66832
T440
P
V
G
F
G
R
R
T
D
P
S
G
D
Y
I
Rat
Rattus norvegicus
Q923I8
594
67204
T440
P
V
G
F
G
R
R
T
D
P
S
G
D
Y
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507425
582
65716
T428
P
V
G
F
G
R
R
T
D
P
S
G
D
F
I
Chicken
Gallus gallus
Q8QG60
582
66078
T431
P
V
G
F
G
R
R
T
D
P
S
G
D
Y
V
Frog
Xenopus laevis
Q75WS4
523
60626
G374
S
F
L
T
K
D
L
G
I
D
W
R
M
G
A
Zebra Danio
Brachydanio rerio
Q4KML2
520
59903
D371
V
A
S
F
L
T
K
D
L
G
L
D
W
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77059
542
62494
L393
T
F
L
T
R
G
G
L
W
Q
S
W
E
H
G
Honey Bee
Apis mellifera
NP_001077099
570
65246
S420
M
W
M
W
L
S
C
S
S
F
F
Q
Q
F
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785873
516
59965
W367
T
Q
L
R
L
E
G
W
I
H
P
L
A
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96524
612
69439
Y423
P
A
L
Q
G
A
K
Y
D
P
E
G
E
Y
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
96.4
N.A.
94.5
93.7
N.A.
88.1
85.8
23.4
25.6
N.A.
37.4
62.3
N.A.
57.6
Protein Similarity:
100
99.6
99.4
97.4
N.A.
96.2
95.7
N.A.
90.8
91
40.9
42.5
N.A.
53.2
74.5
N.A.
69.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
0
6.6
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
0
20
N.A.
20
20
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
8
0
0
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
8
65
8
0
8
58
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
8
0
15
0
0
% E
% Phe:
0
15
0
65
0
0
0
0
0
8
8
0
0
15
8
% F
% Gly:
0
0
58
0
65
8
15
8
0
8
0
65
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% H
% Ile:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
58
% I
% Lys:
0
0
0
0
8
0
15
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
29
0
22
0
8
8
8
0
8
8
0
0
8
% L
% Met:
8
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
65
0
0
0
0
0
0
0
0
65
8
0
0
0
0
% P
% Gln:
0
8
0
8
0
0
0
0
0
8
0
8
8
0
0
% Q
% Arg:
0
0
0
8
8
58
58
0
0
0
0
8
0
15
0
% R
% Ser:
8
0
8
0
0
8
0
8
8
0
65
0
0
0
0
% S
% Thr:
15
0
0
15
0
8
0
58
0
0
0
0
0
0
0
% T
% Val:
8
58
0
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
8
0
8
0
0
0
8
8
0
8
8
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
58
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _