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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRY2
All Species:
15.76
Human Site:
S23
Identified Species:
26.67
UniProt:
Q49AN0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q49AN0
NP_001120929.1
593
66947
S23
A
P
G
T
D
S
A
S
S
V
H
W
F
R
K
Chimpanzee
Pan troglodytes
XP_001160595
593
66872
S23
A
P
G
T
D
G
A
S
S
V
H
W
F
R
K
Rhesus Macaque
Macaca mulatta
XP_001113162
593
66839
S23
A
P
G
T
D
G
A
S
S
V
H
W
F
R
K
Dog
Lupus familis
XP_540761
593
66822
S23
T
A
G
V
D
G
A
S
S
V
H
W
F
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R194
592
66832
S23
M
G
A
D
G
A
S
S
V
H
W
F
R
K
G
Rat
Rattus norvegicus
Q923I8
594
67204
S23
M
G
A
D
G
A
S
S
V
H
W
F
R
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507425
582
65716
P25
X
X
R
L
H
D
N
P
A
L
Q
A
A
L
R
Chicken
Gallus gallus
Q8QG60
582
66078
R23
H
W
F
R
R
G
L
R
L
H
D
N
P
A
L
Frog
Xenopus laevis
Q75WS4
523
60626
L18
L
L
R
N
D
L
R
L
H
D
N
E
V
L
H
Zebra Danio
Brachydanio rerio
Q4KML2
520
59903
L15
I
C
L
L
R
N
D
L
R
L
H
D
N
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77059
542
62494
L23
R
L
H
D
N
P
A
L
L
A
A
L
A
D
K
Honey Bee
Apis mellifera
NP_001077099
570
65246
T23
Y
D
E
G
G
K
H
T
V
H
W
F
R
K
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785873
516
59965
R11
R
K
H
R
S
S
R
R
D
R
E
E
K
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96524
612
69439
A26
D
N
P
A
L
A
A
A
A
H
E
G
S
V
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
96.4
N.A.
94.5
93.7
N.A.
88.1
85.8
23.4
25.6
N.A.
37.4
62.3
N.A.
57.6
Protein Similarity:
100
99.6
99.4
97.4
N.A.
96.2
95.7
N.A.
90.8
91
40.9
42.5
N.A.
53.2
74.5
N.A.
69.1
P-Site Identity:
100
93.3
93.3
73.3
N.A.
6.6
6.6
N.A.
0
0
6.6
6.6
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
73.3
N.A.
33.3
33.3
N.A.
20
0
13.3
20
N.A.
20
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
8
15
8
0
22
43
8
15
8
8
8
15
8
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
22
36
8
8
0
8
8
8
8
0
8
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
15
15
0
8
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
22
29
0
8
% F
% Gly:
0
15
29
8
22
29
0
0
0
0
0
8
0
0
29
% G
% His:
8
0
15
0
8
0
8
0
8
36
36
0
0
0
8
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
8
0
0
0
0
0
0
8
22
36
% K
% Leu:
8
15
8
15
8
8
8
22
15
15
0
8
0
15
8
% L
% Met:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
8
8
8
0
0
0
8
8
8
0
0
% N
% Pro:
0
22
8
0
0
8
0
8
0
0
0
0
8
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
15
0
15
15
15
0
15
15
8
8
0
0
22
29
8
% R
% Ser:
0
0
0
0
8
15
15
43
29
0
0
0
8
0
0
% S
% Thr:
8
0
0
22
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
22
29
0
0
8
8
8
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
22
29
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _