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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRY2
All Species:
24.55
Human Site:
S196
Identified Species:
41.54
UniProt:
Q49AN0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q49AN0
NP_001120929.1
593
66947
S196
V
T
S
Q
Q
M
E
S
C
R
A
E
I
Q
E
Chimpanzee
Pan troglodytes
XP_001160595
593
66872
S196
V
T
S
Q
Q
M
E
S
C
R
A
E
I
Q
E
Rhesus Macaque
Macaca mulatta
XP_001113162
593
66839
S196
V
T
S
Q
Q
M
E
S
C
R
A
E
I
Q
E
Dog
Lupus familis
XP_540761
593
66822
S196
V
T
S
Q
Q
M
E
S
C
R
A
D
I
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9R194
592
66832
S195
V
S
S
Q
Q
M
E
S
C
R
A
E
I
Q
E
Rat
Rattus norvegicus
Q923I8
594
67204
N195
V
S
S
Q
H
M
E
N
C
R
A
E
I
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507425
582
65716
G183
V
T
S
Q
Q
M
E
G
C
K
A
E
I
Q
D
Chicken
Gallus gallus
Q8QG60
582
66078
T186
I
V
S
Q
Q
M
E
T
C
K
V
D
I
Q
E
Frog
Xenopus laevis
Q75WS4
523
60626
D158
R
H
I
S
S
L
P
D
V
Y
T
Q
F
R
K
Zebra Danio
Brachydanio rerio
Q4KML2
520
59903
L155
P
F
S
H
I
G
G
L
P
D
V
Y
T
Q
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77059
542
62494
D177
L
P
P
R
P
T
A
D
A
R
L
E
D
A
T
Honey Bee
Apis mellifera
NP_001077099
570
65246
S195
V
T
S
A
C
V
G
S
A
Y
T
P
L
K
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785873
516
59965
Q151
S
H
T
L
Y
D
P
Q
E
I
L
A
L
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96524
612
69439
I177
P
P
W
R
L
M
P
I
T
A
A
A
E
A
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
96.4
N.A.
94.5
93.7
N.A.
88.1
85.8
23.4
25.6
N.A.
37.4
62.3
N.A.
57.6
Protein Similarity:
100
99.6
99.4
97.4
N.A.
96.2
95.7
N.A.
90.8
91
40.9
42.5
N.A.
53.2
74.5
N.A.
69.1
P-Site Identity:
100
100
100
86.6
N.A.
93.3
80
N.A.
80
60
0
13.3
N.A.
13.3
33.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
93.3
86.6
26.6
13.3
N.A.
26.6
53.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
0
15
8
58
15
0
15
0
% A
% Cys:
0
0
0
0
8
0
0
0
58
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
15
0
8
0
15
8
0
15
% D
% Glu:
0
0
0
0
0
0
58
0
8
0
0
50
8
0
50
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
8
% F
% Gly:
0
0
0
0
0
8
15
8
0
0
0
0
0
0
0
% G
% His:
0
15
0
8
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
8
0
0
8
0
8
0
0
58
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
15
0
0
0
8
8
% K
% Leu:
8
0
0
8
8
8
0
8
0
0
15
0
15
0
0
% L
% Met:
0
0
0
0
0
65
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
8
% N
% Pro:
15
15
8
0
8
0
22
0
8
0
0
8
0
0
0
% P
% Gln:
0
0
0
58
50
0
0
8
0
0
0
8
0
65
0
% Q
% Arg:
8
0
0
15
0
0
0
0
0
50
0
0
0
8
0
% R
% Ser:
8
15
72
8
8
0
0
43
0
0
0
0
0
0
0
% S
% Thr:
0
43
8
0
0
8
0
8
8
0
15
0
8
0
8
% T
% Val:
58
8
0
0
0
8
0
0
8
0
15
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
15
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _