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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRY2 All Species: 30.91
Human Site: S191 Identified Species: 52.31
UniProt: Q49AN0 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q49AN0 NP_001120929.1 593 66947 S191 K P V G L V T S Q Q M E S C R
Chimpanzee Pan troglodytes XP_001160595 593 66872 S191 K P V G S V T S Q Q M E S C R
Rhesus Macaque Macaca mulatta XP_001113162 593 66839 S191 K P V G S V T S Q Q M E S C R
Dog Lupus familis XP_540761 593 66822 S191 K P V G S V T S Q Q M E S C R
Cat Felis silvestris
Mouse Mus musculus Q9R194 592 66832 S190 K P A V A V S S Q Q M E S C R
Rat Rattus norvegicus Q923I8 594 67204 S190 K P V G A V S S Q H M E N C R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507425 582 65716 S178 K P V S C V T S Q Q M E G C K
Chicken Gallus gallus Q8QG60 582 66078 S181 K P V S S I V S Q Q M E T C K
Frog Xenopus laevis Q75WS4 523 60626 I153 E D L P F R H I S S L P D V Y
Zebra Danio Brachydanio rerio Q4KML2 520 59903 S150 H R D D L P F S H I G G L P D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O77059 542 62494 P172 V Q I I G L P P R P T A D A R
Honey Bee Apis mellifera NP_001077099 570 65246 S190 P P V P T V T S A C V G S A Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785873 516 59965 T146 V I S K V S H T L Y D P Q E I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96524 612 69439 W172 S V M L P P P W R L M P I T A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.8 96.4 N.A. 94.5 93.7 N.A. 88.1 85.8 23.4 25.6 N.A. 37.4 62.3 N.A. 57.6
Protein Similarity: 100 99.6 99.4 97.4 N.A. 96.2 95.7 N.A. 90.8 91 40.9 42.5 N.A. 53.2 74.5 N.A. 69.1
P-Site Identity: 100 93.3 93.3 93.3 N.A. 73.3 73.3 N.A. 73.3 60 0 13.3 N.A. 6.6 40 N.A. 0
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 80 86.6 N.A. 80 80 20 13.3 N.A. 26.6 46.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 25.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 44.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 15 0 0 0 8 0 0 8 0 15 8 % A
% Cys: 0 0 0 0 8 0 0 0 0 8 0 0 0 58 0 % C
% Asp: 0 8 8 8 0 0 0 0 0 0 8 0 15 0 8 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 0 58 0 8 0 % E
% Phe: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 36 8 0 0 0 0 0 8 15 8 0 0 % G
% His: 8 0 0 0 0 0 15 0 8 8 0 0 0 0 0 % H
% Ile: 0 8 8 8 0 8 0 8 0 8 0 0 8 0 8 % I
% Lys: 58 0 0 8 0 0 0 0 0 0 0 0 0 0 15 % K
% Leu: 0 0 8 8 15 8 0 0 8 8 8 0 8 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 65 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 8 65 0 15 8 15 15 8 0 8 0 22 0 8 0 % P
% Gln: 0 8 0 0 0 0 0 0 58 50 0 0 8 0 0 % Q
% Arg: 0 8 0 0 0 8 0 0 15 0 0 0 0 0 50 % R
% Ser: 8 0 8 15 29 8 15 72 8 8 0 0 43 0 0 % S
% Thr: 0 0 0 0 8 0 43 8 0 0 8 0 8 8 0 % T
% Val: 15 8 58 8 8 58 8 0 0 0 8 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _