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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KBTBD12
All Species:
23.03
Human Site:
Y378
Identified Species:
46.06
UniProt:
Q3ZCT8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3ZCT8
NP_997218.2
623
71096
Y378
T
A
E
F
R
E
L
Y
A
L
G
S
I
H
N
Chimpanzee
Pan troglodytes
XP_001141101
457
49844
T237
I
K
N
Q
Y
L
I
T
N
C
V
D
K
Y
S
Rhesus Macaque
Macaca mulatta
XP_001098649
623
71122
Y378
T
A
E
F
R
E
L
Y
A
L
G
S
I
H
N
Dog
Lupus familis
XP_541739
623
71128
Y378
T
A
E
F
R
E
L
Y
A
L
G
S
V
H
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9D618
625
71222
Y376
T
A
E
F
R
E
L
Y
A
L
G
S
I
H
N
Rat
Rattus norvegicus
Q8K430
640
69714
T411
V
E
S
Y
D
P
V
T
N
T
W
Q
P
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520793
361
41204
K141
V
G
I
Y
Y
F
A
K
H
I
V
A
E
D
L
Chicken
Gallus gallus
XP_425160
619
70418
Y378
T
A
Q
F
R
E
L
Y
A
L
G
T
V
H
N
Frog
Xenopus laevis
Q5U504
614
69682
P389
D
S
D
W
L
G
M
P
P
V
P
S
A
R
C
Zebra Danio
Brachydanio rerio
Q3ZB90
623
70237
Y382
S
A
E
Y
R
D
S
Y
A
L
S
S
L
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
L371
V
A
V
L
N
D
L
L
Y
A
V
G
G
H
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788235
595
67022
V357
M
K
H
S
R
R
G
V
G
V
A
I
V
D
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.5
98.2
94
N.A.
91.3
26
N.A.
47.5
74.9
24
56.5
N.A.
27.7
N.A.
N.A.
28.2
Protein Similarity:
100
57.7
99.1
98.3
N.A.
95.3
44.5
N.A.
52.9
88.7
48.3
75.2
N.A.
46.5
N.A.
N.A.
47.3
P-Site Identity:
100
0
100
93.3
N.A.
100
0
N.A.
0
80
6.6
46.6
N.A.
20
N.A.
N.A.
13.3
P-Site Similarity:
100
20
100
100
N.A.
100
13.3
N.A.
20
100
40
73.3
N.A.
33.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
59
0
0
0
0
9
0
50
9
9
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% C
% Asp:
9
0
9
0
9
17
0
0
0
0
0
9
0
17
9
% D
% Glu:
0
9
42
0
0
42
0
0
0
0
0
0
9
9
9
% E
% Phe:
0
0
0
42
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
9
9
0
9
0
42
9
9
9
0
% G
% His:
0
0
9
0
0
0
0
0
9
0
0
0
0
50
0
% H
% Ile:
9
0
9
0
0
0
9
0
0
9
0
9
25
0
0
% I
% Lys:
0
17
0
0
0
0
0
9
0
0
0
0
9
0
0
% K
% Leu:
0
0
0
9
9
9
50
9
0
50
0
0
9
0
9
% L
% Met:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
0
0
17
0
0
0
0
0
50
% N
% Pro:
0
0
0
0
0
9
0
9
9
0
9
0
9
0
0
% P
% Gln:
0
0
9
9
0
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
0
0
59
9
0
0
0
0
0
0
0
9
0
% R
% Ser:
9
9
9
9
0
0
9
0
0
0
9
50
0
0
9
% S
% Thr:
42
0
0
0
0
0
0
17
0
9
0
9
0
0
0
% T
% Val:
25
0
9
0
0
0
9
9
0
17
25
0
25
0
9
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
25
17
0
0
50
9
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _