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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUBB8
All Species:
49.7
Human Site:
T166
Identified Species:
99.39
UniProt:
Q3ZCM7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3ZCM7
NP_817124.1
444
49776
T166
Y
P
D
R
I
I
N
T
F
S
I
L
P
S
P
Chimpanzee
Pan troglodytes
Q8WP14
444
49773
T166
Y
P
D
R
I
I
N
T
F
S
I
L
P
S
P
Rhesus Macaque
Macaca mulatta
XP_001104203
446
50230
T166
Y
P
D
R
I
I
N
T
F
S
I
L
P
S
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERD7
450
50400
T166
Y
P
D
R
I
M
N
T
F
S
V
V
P
S
P
Rat
Rattus norvegicus
Q6P9T8
445
49782
T166
Y
P
D
R
I
M
N
T
F
S
V
V
P
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P32882
445
49935
T166
Y
P
D
R
I
M
N
T
F
S
V
M
P
S
P
Frog
Xenopus laevis
P30883
445
49797
T166
Y
P
D
R
I
M
N
T
F
S
V
V
P
S
P
Zebra Danio
Brachydanio rerio
NP_942104
445
49768
T166
Y
P
D
R
I
M
N
T
F
S
V
V
P
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24560
447
50129
T166
Y
P
D
R
I
M
N
T
Y
S
V
V
P
S
P
Honey Bee
Apis mellifera
XP_392313
447
50157
T166
Y
P
D
R
I
M
N
T
Y
S
V
V
P
S
P
Nematode Worm
Caenorhab. elegans
P41937
444
49782
T166
Y
P
D
R
I
M
M
T
F
S
V
V
P
S
P
Sea Urchin
Strong. purpuratus
XP_791790
447
50098
T166
Y
P
D
R
I
M
N
T
F
S
V
V
P
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.1
N.A.
N.A.
85.1
90.3
N.A.
N.A.
88.5
90.1
89.4
N.A.
88.5
88.1
86.2
90.1
Protein Similarity:
100
99.7
98.2
N.A.
N.A.
91.7
95.5
N.A.
N.A.
95
95
95.5
N.A.
94.4
94.4
94.3
95.3
P-Site Identity:
100
100
100
N.A.
N.A.
80
80
N.A.
N.A.
80
80
80
N.A.
73.3
73.3
73.3
80
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
100
100
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
84
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
100
25
0
0
0
0
25
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% L
% Met:
0
0
0
0
0
75
9
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
92
0
0
0
0
0
0
0
0
% N
% Pro:
0
100
0
0
0
0
0
0
0
0
0
0
100
0
100
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
100
0
0
0
100
0
% S
% Thr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
75
67
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
100
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _