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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADCK5 All Species: 45.15
Human Site: Y386 Identified Species: 76.41
UniProt: Q3MIX3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3MIX3 NP_777582.3 580 65897 Y386 V L L D H G L Y Q F L E E K D
Chimpanzee Pan troglodytes XP_001157317 580 65781 Y386 V L L D H G L Y Q F L E E K D
Rhesus Macaque Macaca mulatta XP_001104139 523 59652 Y335 V L L D H G L Y Q V L T E E F
Dog Lupus familis XP_539216 624 71219 Y430 V L L D H G L Y Q F L D E K D
Cat Felis silvestris
Mouse Mus musculus Q80V03 582 66636 Y386 V L L D H G L Y Q F L D E K D
Rat Rattus norvegicus NP_001129270 582 66734 Y386 V L L D H G L Y Q F L D E K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507044 482 54419 E337 Q E L D F E N E G R N A E R C
Chicken Gallus gallus Q5ZMT7 519 59182 Y332 I L L D H G L Y Q V L S E S F
Frog Xenopus laevis Q6INL7 520 59525 Y335 I L L D H G L Y Q V L T E S F
Zebra Danio Brachydanio rerio XP_001341554 579 66788 Y386 V L L D H G L Y E H L S K S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648446 557 64196 Y361 I L L D H G L Y E E L P Q N V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181542 582 67255 Y422 I V L D H G L Y E E V T P E I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04212 538 60900 Y358 V I L D H G L Y K E L D F N T
Baker's Yeast Sacchar. cerevisiae Q06567 569 65899 Y376 V L F D H G L Y R Y P S T R T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 34.4 77 N.A. 80.5 79.3 N.A. 56.2 32.2 32.9 60.5 N.A. 38.9 N.A. N.A. 41.4
Protein Similarity: 100 99.6 51.7 83.3 N.A. 89 88.1 N.A. 63.7 49.6 51.5 76.5 N.A. 57.2 N.A. N.A. 60.4
P-Site Identity: 100 100 73.3 93.3 N.A. 93.3 93.3 N.A. 20 66.6 66.6 66.6 N.A. 53.3 N.A. N.A. 40
P-Site Similarity: 100 100 80 100 N.A. 100 100 N.A. 26.6 73.3 73.3 80 N.A. 73.3 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. 32.7 25.1 N.A.
Protein Similarity: N.A. N.A. N.A. 51.7 45.8 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 100 0 0 0 0 0 0 0 29 0 0 43 % D
% Glu: 0 8 0 0 0 8 0 8 22 22 0 15 65 15 0 % E
% Phe: 0 0 8 0 8 0 0 0 0 36 0 0 8 0 22 % F
% Gly: 0 0 0 0 0 93 0 0 8 0 0 0 0 0 0 % G
% His: 0 0 0 0 93 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 29 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 0 0 8 36 0 % K
% Leu: 0 79 93 0 0 0 93 0 0 0 79 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 8 0 0 15 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 8 8 8 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 58 0 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 8 0 0 0 15 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 22 0 22 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 22 8 0 15 % T
% Val: 65 8 0 0 0 0 0 0 0 22 8 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 93 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _